OBJECTIVE Symptoms of salivary gland dysfunction frequently develop after radioactive iodine (RAI) therapy, but have generally not been correlated with assessment of salivary gland functioning. The aim of this study was to determine whether there was a correlation between salivary symptoms and salivary functioning as assessed by salivary scan parameters. METHODS This was a non-randomized obse...

Purpose: Radiography, Sailography, Scintigraphy, Computerized Tomography, MRI and Ultrasonography are the available diagnostic aids to diagnose salivary gland lesions. All the diagnostic aids have their own limitations in the diagnosis of salivary gland diseases. The advantage of ultrasonography in the diagnosis of salivary gland enlargements is its ease to use, less expensive, less time consum...

UNLABELLED During esophageal acid clearance, salivation plays an important role in defending the esophageal mucosa. Nizatidine, a histamine H2 receptor antagonist, inhibits acetylcholine esterase, with a resultant increase in acetylcholine. We experienced a patient with gastroesophageal reflux disease (GERD) and impaired salivary secretion who has been successfully treated with nizatidine. CA...

The aim of this study was to evaluate the effects of the first radioactive iodine (I) therapy on functions of salivary glands in patients with differentiated thyroid carcinoma (DTC).There were 36 consented patients with DTC enrolled in this study, who received 3.7 GBq (100mCi) I for ablation after total thyroidectomy. Salivary gland function was assessed using salivary gland scintigraphy in two...

Background: Iodine-131 (I-131) is an effective treatment for differentiated thyroid carcinomas (DTC) after surgery. Salivary and lacrimal gland dysfunction has been described in patients receiving high doses of 1-131 due to radiation damage to salivary and lacrimal glands. Objective: This prospective study was conducted to determine the short term effect of oral 1-131 therapy administered to th...

UNLABELLED Salivary gland dysfunction is one of the common side effects of high-dose radioiodine therapy for thyroid cancer. The purpose of this study was to determine whether an early start of sucking lemon candy decreases salivary gland injury after radioiodine therapy. METHODS The incidence of the side effects of radioiodine therapy on the salivary glands was prospectively and longitudinal...

OBJECTIVE To characterise the psychological profiles of Sjögren's syndrome (SS) and patients with sicca symptoms but without SS; to find predictors for salivary gland function; to evaluate salivary scintigraphy as a method to differentiate between SS and patients with sicca symptoms but without SS. PATIENTS AND METHODS Psychological tests (Medical Outcomes Study Short Form General Health Surv...

UNLABELLED Salivary gland dysfunction has been described in patients undergoing radioiodine therapy but associated lacrimal gland dysfunction (sicca syndrome) has never been reported. We conducted a prospective cohort study with follow-up for up to 3 y in a tertiary care university center to determine the prevalence of sicca syndrome in patients after high-dose radioiodine treatment. METHODS ...

The purpose of this study was to assess the effect of levocetirizine (xyzal) on salivary glands function in patients with allergic rhinitis using technetium-99m pertechnetate ((99m)Tc-P) salivary gland scintigraphy. The study population consisted of 67 patients with allergic rhinitis and 31 healthy controls (14 males and 17 females, mean age 30.1+/-6.8 years). The patients were divided into two...

BACKGROUND The purpose of this study was to prospectively evaluate the scintigraphic results on patients who undergo intensity-modulated radiotherapy (IMRT) to investigate the tolerance doses for the salivary glands. METHODS Salivary scintigraphy was performed on 35 patients with head and neck cancer before the beginning of radiotherapy (RT), and then at 6 weeks and again at 3 months after th...