We tested the hypothesis that overweight/obese men aged 50-70 years will have a greater salivary cortisol, salivary alpha amylase and heart rate (HR) responses to psychological stress compared with age matched lean men. Lean (BMI=20-25 kg/m(2); n=19) and overweight/obese (BMI=27-35 kg/m(2); n=17) men (50-70 years) were subjected to a well-characterised psychological stress (Trier Social Stress ...

INTRODUCTION There is a pressing need to identify diagnostic testing for Cushing's syndrome that can be achieved with ease and at low cost. This study aimed to explore the usefulness of late-night and post-overnight 1-mg dexamethasone suppression salivary cortisone, as measured by liquid chromatography-tandem mass spectrometry, for investigation of hypercortisolism. METHODS Salivary cortisone...

INTRODUCTION The mesurement of midnight salivary cortisol provides the most sensitive method for screening of Cushing's sendrome. However the clinical significance of spectral error is the requirement for determination of normal reference values in each population for each test, which will be used as the diagnostic method. Salivary cortisol levels may be affected by individual factors such as n...

background: chronic fatigue syndrome (cfs) is a complex condition involving severe fatigue and disabling musculoskeletal and cognitive symptoms. we reported that 6, 12 and 24 months following infectious mononucleosis (im), 13%, 7% and 4% of adolescents, respectively, met criteria for cfs. whether endocrinologic or immunologic dysfunction accompanies cfs is unclear. objectives: to determine if s...

The present study evaluates the use of salivary cortisol concentration as a physiological index of the stress level among nurses on their work day and day off and correlates it with the questionnaire used to measure occupational stress in nurses (Inventário de Estresse em Enfermeiros - IEE). This is a comparative, cross-sectional descriptive study in which sociodemographic data, IEE results and...

background noise exposure is known as a risk factor for hearing loss and one of its effects is noise-induced stress. cortisol as a stress hormone is used in noise-induced stress assessments. objectives the aim of this study was to measure and compare saliva cortisol concentrations in the morning and evening in normal work day and rest day in both case and control groups and to assess the associ...

OBJECTIVE The adrenal excretion of cortisol in animals is dependent on the production of corticotropin-releasing factor in the paraventricular nucleus of the hypothalamus. The a priori hypothesis of this study was that hypothalamic regional cerebral blood flow (rCBF) would correlate positively with salivary cortisol levels in patients with social anxiety disorder (SAD) during anxiety provocatio...

coping style is one of the substantial factors influencing sport achievements insport competitions. the main aim of the present study was to examine the effect ofsport stress coping styles on sources of acute stress and salivary cortisol inwrestlers. with regard to the criteria and variables of this study, 30 out of 270active national wrestlers participated according to the cut-off point of cop...

BACKGROUND Hypothalamic-pituitary-adrenal (HPA) axis abnormalities have been reported in bipolar disorder and also in suicidal behavior, but few studies have examined the relationship between suicidal behaviors and the HPA axis function in bipolar disorder, attending to and minimizing confounding factors. We compare HPA axis activity in bipolar individuals with and without suicidal behavior and...

Previous research has noted both high and low baseline cortisol levels in anxious personality styles. We examined the relations among shyness, baseline salivary cortisol, and resting heart rate in a non-clinical sample of 10-year-old children. As predicted, shyness was positively correlated with baseline salivary cortisol and resting heart rate, replicating and extending earlier work with presc...