Objective: To compare the outcome of addition nebulized magnesium sulphate to standard treatment in children with acute severe asthma. Methodology: The trial was undertaken at emergency Paediatrics Department, Federal Government Polyclinic (Post Graduate Medical Institute), Islamabad from 1st April 30th September 2019.Children between 1 12 years age asthma were initially salbutamol thrice and i...

K E Y W O R D S environmental controlled light microscopy, pharmaceutical solids, amorphous transitions, stability, environmental control stage A C K N O W L E D G E M E N T S The authors wish to thank Sebastian Kaerger for his help in producing the spray dried salbutamol sulphate. A U T H O R D E TA I L S Dr Paul M. Young, Pharmaceutical Technology Research Group, Department of Pharmacy and Ph...

Gittleman syndrome (GS) is autosomal recessive renal tubulopathy caused by mutation of genes encoding protein for sodium chloride cotransporter and magnesium channel in the distal convoluted tubule.1 We present case a-20-years old female patient admitted our Internal Medicine Department recurrent hypokalaemia. She presented with quadriparesis. There was no history taking inhaled salbutamol, ins...

In vivo assessment and identification of aneuploidy are important phases of genotoxicity evaluation. Considerable effort has been devoted to assess the utility of the existing bioassays and to develop simpler techniques for identifying environmental aneugens. Salbutamol sulphate--an antiasthmatic drug was tested for its spindle damaging effects in bone marrow cells of mice using an in vivo tech...

its extent of spread. Being aware that multiple simultaneous CSF leaks are often present, two separate epidurals may lead to a more complete dural tamponade and better sealing in the upper cervical meninges. Injection at two separate sites may decrease the possibility of spinal compression from a large amount of blood and guarantee a more uniform distribution over the meninges. In conclusion, s...

The objective of the present study was to prepare the fast disintegrating tablet of Salbutamol Sulphate, Cetirizine Hydrochloride in combined tablet dosage form for respiratory disorders such as bronchitis, asthma, and coughing for pediatrics and geriatrics. The tablets were prepared by direct compression technique. Superdisintegrant such as Sodium Starch Glycolate was optimized as 4% on the ba...