Saffron is one of the highly exotic spices known for traditional values and antiquity. It is used for home décor besides serving as a colorant flavor and is widely known for medicinal value. Over the last few years, saffron has garnered a lot of interest due to its anti-cancer, anti-mutagenic, anti-oxidant and immunomodulatory properties. Integration of systems biology approaches with wide appl...

The difficult cultivation of the saffron plant (Crocus Sativus L.) make the spice of the same name made from its dried stigmas very valuable. It is estimated that some 75,000 blossoms or 225,000 hand-picked stigmas are required to make a single pound of saffron, which explains why it is the world's most expensive spice. The aim of this study was to identify ways of increasing the fertility and ...

The effects of chemical and organic fertilizers on saffron (Crocus sativus) were studied in a field experiment using a complete randomized block design with three replications at ferdowsi university of Mashhad. Fertilizers applied were N, P, K, NP, NK, PK, NPK, cow, sheep and chicken manure. The amount of chemical fertilizer applied were 50, 30, 30, 48, 48, 36, 66 kg/ha for N, P, K, NP, NK, PK,...

antimicrobial activity of different parts of croccus sativus l. (saffron) including stigma, stamen, leaves and colora, extracted by various solvents, were tested against different bacteria (microccucos luteus, staphylococcus epidermitis, staphylococcus aureus and e. coli) and fungi (candida albicans, aspergillus niger and cladospourium sp) by cup plate diffusion method. minimal inhibitory conce...

BACKGROUND Saffron (Crocus sativus L.) is a common but very expensive herbal medicine. As an important traditional medicine, it has an outstanding effect in treating irregular and painful menstruation. Recently, the over-demand tendency of saffron results in an unusual phenomenon in the medicinal markets. Adulterants and saffron-like substitutes are intentionally mixed into medicinal markets an...

INTRODUCTION Saffron has been suggested to have inhibitory effects on tumoral cells. We evaluated the cytotoxic effect of aqueous extract of saffron on human transitional cell carcinoma (TCC) and mouse non-neoplastic fibroblast cell lines. MATERIALS AND METHODS Human TCC 5637 cell line and mouse fibroblast cell line (L929) were cultivated and incubated with different concentrations of aqueous...

Saffron (Zaaferan), botanical name Crocus sativus, is the most expensive spice in the world. It is derived from the dried stigma and pistil of the purple saffron crocus flowers. Iran is the largest saffron producer accounting for more than 80% of the world's production. Saffron contains an aeroallergen that causes reactive respiratory allergic reactions in atopic subjects. IgG antibody to aller...

BACKGROUND Saffron and its constituents are widely used around the world as a spice and medicinal plant. Different constituents in medicinal herbs are thought to have the potential to induce useful and/or adverse effects. So, efforts have been made to find the best and most valuable tools to reduce their adverse effects. OBJECTIVES According to Iranian traditional medicine (ITM), it is believ...

BACKGROUND Lipid transfer proteins (LTPs) are relevant allergens, and have recently been proposed as model plant allergens from fruit, vegetables, seeds, and pollens. However, no LTP spice allergen has been characterized to date. OBJECTIVES To identify and isolate saffron LTPs and to explore their relevance in saffron allergy. METHODS Six patients with rhinitis and positive skin prick test ...

BACKGROUND The cultivation of saffron is expanding through the southeast of Iran, and allergy to saffron pollen occurs in workers involved in processing this plant. We aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. METHODS The N-terminal amino acid sequence of Cro s 1, an allergen from saffron...