Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. We aim to determine the sources of seizure-induced ROS and ...

Xanthine oxidase plays crucial roles in the production of reactive oxygen species (ROS), and uric acid in blood which may lead to gout, one of the oldest known forms of arthritis amongst humans. Summer savory (Satureja hortensis L.) a medicinal/spice exhibits antioxidant activity, but unknown effects on xanthine oxidase activity. Here, for the first time, we examined the effects of S. hortensis...

in this study, the effect of salicylic acid (sa) on root knot nematode (meloidogyne javanica) pathogenicity and induction of some defense mechanisms such as polyphenol oxidase enzyme activity and total phenol accumulation were investigated in greenhouse conditions. we demonstrated that application of 5mm salicylic acid through foliar spray could induce resistance against m. javanica in tomato. ...

objective: polyphenol oxidase or ppo (ec 1.14.18.1) is considered the enzyme responsible for quality deterioration and browning in different fruits during postharvest period. the objective of this study was to evaluate the antibrowning (inhibition of polyphenol oxidase activity) effect of cysteine, ascorbic acid, citric acid, kojic acid and glycine at two different ph (6 and 7) in  hawthorn. me...

The endogenous reactive oxygen species ("ROS") formation is associated with many pathologic states such as inflammatory diseases, neurodegenerative diseases, brain and heart ischemic injuries, cancer, and aging. The purpose of this study was to investigate the endogenous sources for "ROS" formation in intact isolated rat hepatocytes, in particular, peroxisomal oxidases, monoamine oxidase, xanth...

seizure activity has been proposed to result in the generation of reactive oxygen species (ros), which then contribute to seizure-induced neuronal damage and eventually cell death. although the mechanisms of seizure-induced ros generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. we aim to determine the sources of seizure-induced ros and ...

Allopurinol, the xanthine oxidase inhibitor, is the only drug available for the treatment of gout. We examined the xanthine oxidase inhibitory activity of some commercially available flavonoids such asepigallocatechin, acacatechin, myricetin, naringenin, daidzein and glycitein by virtual screening and in-vitro studies. The interacting residues within the complex model and their contact types we...

Allopurinol, the xanthine oxidase inhibitor, is the only drug available for the treatment of gout. We examined the xanthine oxidase inhibitory activity of some commercially available flavonoids such asepigallocatechin, acacatechin, myricetin, naringenin, daidzein and glycitein by virtual screening and in-vitro studies. The interacting residues within the complex model and their contact types we...

allopurinol, the xanthine oxidase inhibitor, is the only drug available for the treatment of gout. we examined the xanthine oxidase inhibitory activity of some commercially available flavonoids such asepigallocatechin, acacatechin, myricetin, naringenin, daidzein and glycitein by virtual screening and in-vitro studies. the interacting residues within the complex model and their contact types we...

glucose, as the major energy source in cellular metabolism, plays an important role in the natural growth of cells. herein, a simple, rapid and low-cost method for the glucose determination by utilizing glucose oxidase and cdte/thioglycolic acid (tga) quantum dots (qds) on a thin layer chromatography (tlc) plate has been described. the detection was based on the combination of the glucose enzym...