background : seborrheic keratosis is a common, benign skin tumor. numerous reports have shown its possibility of malignant transformation. this study was designed to demonstrate the occurrence of concomitant seborrheic keratosis and skin cancers. methods : data was retrospectively reviewed from all patients with a diagnosis of seborrheic keratosis in pathology department of alzahra hospital and...

introduction: behcet's disease is a chronic disease with multisystem involvement characterized clinically by oral and genital aphthae, cutaneous lesions and ophthalmologic, neurologic and gastrointestinal manifestation. nervous system involvement occurs in 5.3 – 30% of patients, mostly in brain stem and basal ganglia. the common manifestations are pyramidal signs, central nervous plegia, p...

background: metal ions effect on homeostasis of alzheimer’s disease (ad) patients. the aim of this study was to assess the metal ions (iron, zinc and copper) and cbc in patients with ad in comparison with normal range. methods: the samples of study were 17 patients with ad in tehran’s aging centers in 2015, selected as an access sample. blood samples were analyzed in a pathobiology laboratory. ...

background: this study was designed to determine and compare the stress, anxiety and depression levels in behcet’s disease (bd) patients and a control group of normal individuals. materials and methods: one-hundred and six patients with bd were selected as cases and controls were 106 age- and sex-matched participants referred to the shiraz dental school clinics due to dental problems. we collec...

six patients with disseminated hodgkin's disease resistant to mopp (mechlorethamine, vincristine, procarbazine and prednisolone), and abvd (adriamycin, bleomycin, vinblastine and dacarbazine) chemotherapy were treated with high-dose chemotherapy and autologous marrow transplantation. the patients first underwent marrow aspiration and storage for subsequent autologous bone marrow transplant...

objective(s): the aim of this study is to evaluate the role of pet-ct in identification of different patterns of extranodal involvement in hodgkin’s disease (hd) and non-hodgkin’s lymphoma (nhl) and to enlist the common sites of extranodal involvement in each histological type and compare our results with the existing literature. methods: in this retrospective study of 281 cases of lymphomas of...

background there are great variations in the incidence and prevalence of inflammatory bowel diseases (ibd) among different populations. epidemiologic studies mainly come from north america and europe. studies from iran are mostly data on the adult population from the northern region of the country. methods medical records of 37 pediatric patients (≤ 18 years of age) admitted in the pediatric ga...

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donepezil, a member of the acetylcholinesterase inhibitor family, is approved for management of cognitive impairments as well as behavioral complications in patients with neurodegenerative alzheimer's disease. generally, donepezil is regarded as a safe medication in patients with alzheimer's disease although there have been reports of several minor adverse events including gastrointestinal dist...

background: alzheimer’s disease (ad) is a progressive neurodegenerative disease and nowadays the role of endothelial cell (ec) injury has been proposed in pathological process in ad. peroxisome proliferator‑activated receptor‑γ (ppar‑γ) agonist has anti‑inflammatory properties through activation in glial cells and improves vascular function and prevent atherosclerotic disease progression. the a...