We evaluated the efficacy of a recombinant surfactant protein-C (rSP-C) surfactant in vitro and in vivo, using ventilated preterm lambs and rabbits. The surface tension measured with a Wilhelmy balance of the rSP-C surfactant was lower than the surface tension of natural sheep surfactant (containing SP-B and SP-C). The rSP-C and natural surfactants were equivalently sensitive to inhibition by p...

Identification of allelic variability at the two major loci (Sd and Rsp) that interact to cause sperm dysfunction in Segregation distorter (SD) males of D. melanogaster has been hampered by the difficulty in separating the elements recombinationally. In addition, small differences in the strength of Sd alleles or sensitivities of Rsp alleles to Sd are difficult to measure against background gen...

The current state of the art in RDF Stream Processing (RSP) proposes several models and implementations to combine Semantic Web technologies with Data Stream Management System (DSMS) operators like windows. Meanwhile, only a few solutions combine Semantic Web and Complex Event Processing (CEP), which includes relevant features, such as identifying sequences of events in streams. Current RSP que...

The Responder (Rsp) locus in Drosophila melanogaster is the target locus of segregation distortion and is known to be comprised of a tandem array of 120-bp repetitive sequences. In this study, we first determined the large scale molecular structure of the Rsp locus, which extends over a region of 600 kb on the standard sensitive (cn bw) chromosome. Within the region, small Rsp repeat arrays are...

Plants utilize proteins containing nucleotide binding site (NB) and leucine-rich repeat (LRR) domains as intracellular innate immune receptors to recognize pathogens and initiate defense responses. Since mis-activation of defense responses can lead to tissue damage and even developmental arrest, proper regulation of NB-LRR protein signaling is critical. RAR1, SGT1, and HSP90 act as regulatory c...

This work presents remote store programming (RSP), an instance of the reflective memory model designed to be incrementally supportable on multicores that support loads and stores. To demonstrate the value of RSP, its performance is compared to that of both shared and distributed memory approaches using the TILEPro64 multicore processor. RSP is shown to be as much as 1.76× faster than distribute...

Due to the growing need to timely process and derive valuable information and knowledge from data produced in the Semantic Web, RDF stream processing (RSP) has emerged as an important research domain. In this paper, we describe the design of an RSP engine that is built upon state of the art Big Data frameworks, namely Apache Kafka and Apache Spark. Together, they support the implementation of a...

We used physical and pharmacokinetic modeling to estimate personal exposures to respirable particle (RSP) and carcinogenic particulate polycyclic aromatic hydrocarbon (PPAH) air pollution from second-hand smoke (SHS) from the increase in urinary cotinine of eight patrons of three bars in Bismarck, North Dakota. We compared SHS-RSP levels to the U.S. Air Quality Index (AQI), used to forecast out...

RDF and SPARQL are established standards for data interchange and querying on the Web. While they have been shown to be useful and applicable in many scenarios, they are not sufficiently adequate for dealing with streams of data and their intrinsic continuous nature. In the last years data and query languages have been proposed to extend both RDF and SPARQL for streams and continuous processing...

To understand the hippocampus, it is necessary to understand the subiculum. Unlike other hippocampal subfields, the subiculum projects to almost all distal hippocampal targets, highlighting its critical importance for external networks. The present studies, in male rats and mice, reveal a new category of dorsal subiculum neurons that innervate both the mammillary bodies (MBs) and the retrosplen...