نتایج جستجو برای: rs9939609 polymorphism

تعداد نتایج: 107470  

Journal: :iranian journal of public health 0
ying liu *, yongxia chen

background: we aimed to elucidate the association between fat mass and obesity associated gene (fto) polymorphism and the risk of polycystic ovary syndrome (pcos) by meta-analysis. methods: we searched pubmed and embase databases to find the relevant studies. odds ratios (ors) and their corresponding 95% confidence intervals (cis) were used for pooled analysis. statistical analyses were carried...

2014
Xianli Cai Chibo Liu Sihua Mou

AIMS Many studies have investigated the relationship between FTO gene polymorphism and polycystic ovary syndrome (PCOS) susceptibility but revealed mixed results. In this study, we aimed to perform a meta-analysis to clarify this association. METHODS Published literature from PubMed, Embase and CNKI was retrieved. Meta-analysis was performed to calculate pooled odds ratio (OR) with 95% confid...

2011
Josefin A. Jacobsson Markus Sällman Almén Christian Benedict Lilia A. Hedberg Karl Michaëlsson Samantha Brooks Joel Kullberg Tomas Axelsson Lars Johansson Håkan Ahlström Robert Fredriksson Lars Lind Helgi B. Schiöth

BACKGROUND The rs9939609 single-nucleotide polymorphism (SNP) in the fat mass and obesity (FTO) gene has previously been associated with higher BMI levels in children and young adults. In contrast, this association was not found in elderly men. BMI is a measure of overweight in relation to the individuals' height, but offers no insight into the regional body fat composition or distribution. O...

2015
Siska Mayasari Lubis Jose Batubara Harun Alrasyid Damanik Miswar Fattah

Methods We conducted a case control study in ten elementary schools in Medan, North Sumatera, Indonesia. Case group (n=105) were children with early onset obesity and control group (n=55) were normal weight children. The inclusion criteria were Bataknese and Chinese children, aged 6-12 years with early onset obesity. We examined body weight and height, body mass index, waist circumference. Geno...

Journal: :Pediatrics 2014
Francisco B Ortega Jonatan R Ruiz Idoia Labayen David Martínez-Gómez Germán Vicente-Rodriguez Magdalena Cuenca-García Luis Gracia-Marco Yannis Manios Laurent Beghin Dénes Molnar Angela Polito Kurt Widhalm Ascensión Marcos Marcela González-Gross Anthony Kafatos Christina Breidenassel Luis A Moreno Michael Sjöström Manuel J Castillo

OBJECTIVE Coordinated European projects relying on standardized methods are needed to identify health inequalities across Europe. This study aimed to compare fitness, fatness, and cardiometabolic risk between urban adolescents from the south and center-north of Europe and to explore whether physical activity (PA) and other factors might explain these differences. METHODS The Healthy Lifestyle...

Journal: :Acta obstetricia et gynecologica Scandinavica 2016
Jaroslav A Hubacek Dita Kasparova Dana Dlouha Hynek Pikhart Martin Bobak Tomas Fait

We read with interest the study of Andraweera et al., published recently in Acta Obstetricia et Gynecologica Scandinavica [1], reporting a strong association between maternal FTO (rs9939609) genotype and the risk of miscarriage and recurrent pregnancy loss. Inspired by the report, we attempted to test a related hypothesis that the FTO polymorphism is associated with spontaneous abortions when t...

2015
Marcus Bandstein Bernd Schultes Barbara Ernst Martin Thurnheer Helgi B. Schiöth Christian Benedict

BACKGROUND A recent study in children demonstrated that the rs9939609 single-nucleotide polymorphism in the fat mass and obesity (FTO) gene influences prospective weight gain, however, only in those who were vitamin D-deficient. If this might also be the case for Roux-en-Y gastric bypass (RYGB), surgery-induced weight loss is however unknown. The objective of this study is to examine if the mag...

2012
Tomoka Kawajiri Yoneatsu Osaki Takuji Kishimoto

To investigate whether gene polymorphism of the fat mass and obesity associated gene (FTO) is associated with metabolic syndrome (MS), we used two MS criteria, the National Cholesterol Education Program-Adult Treatment panel III (NCEP-ATPIII) definition in 2003 and the Japanese definition in 2005. Subjects were respectively 859 and 865 Japanese workers at a company in Shimane Prefecture, Japan....

2017
Ying LIU Yongxia CHEN

BACKGROUND We aimed to elucidate the association between fat mass and obesity associated gene (FTO) polymorphism and the risk of polycystic ovary syndrome (PCOS) by meta-analysis. METHODS We searched PubMed and Embase databases to find the relevant studies. Odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) were used for pooled analysis. Statistical analyses were carried...

Journal: :Hormone research in paediatrics 2014
Thomas Reinehr Barbara Wolters Christian L Roth Anke Hinney

OBJECTIVE Polymorphisms in intron 1 of the 'fat mass and obesity-associated' (FTO) gene are associated with weight status. We hypothesized that the risk allele at a polymorphism in intron 1 of FTO is associated with weight regain after end of lifestyle intervention. METHODS We longitudinally analyzed the changes of weight status as BMI-SDS in 346 unrelated overweight children (mean age 10.6 ±...

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