Sulfamates are important functional groups in certain areas of current medicinal chemistry and drug development. Alcohols and phenols are generally converted into the corresponding primary sulfamates (ROSO(2)NH(2) and ArOSO(2)NH(2), respectively) by reaction with sulfamoyl chloride (H(2)NSO(2)Cl). The lability of the O-sulfamate group, especially to basic conditions, usually restricts this meth...

Cytochrome P-450 was purified to a content of over 17 nmoles Sunmarc per mg of protein from liver microsomes of phenobarbital-treated rabbits by fractionation with polyethylene glycol 6000, DEAE-cellulose colunn chromatography, and hydroxylapatite column chromatography in the presence of Renex 690, a nonionic detergent. The purified preparation exhibited a single polypeptide band (molecular wei...

no. 424; Session G4.44 [email protected] EFFECT OF SMALL-HERD CLUSTERING ON THE GENETIC CONNECTEDNESS OF THE PORTUGUESE HOLSTEIN CATTLE POPULATION J.Vasconcelos and J.Carvalheira Centro Investigação em Biodiversidade e Recursos Genéticos (CIBIO), Universidade do Porto, Rua Padre Armando Quintas, 4485-661 Vairão, PORTUGAL, ICBAS-Universidade do Porto INTRODUCTION Accuracy of genetic evaluat...

Braz J Cardiovasc Surg | Rev Bras Cir Cardiovasc he last 12 months have been of deep losses for the Brazilian cardiovascular surgery. Distinguished and competent professionals, fundamental to the consolidation and advancement of the specialty in our country have left us, after serving brilliantly their career in this world. On July 10, 2014, Dr. Geraldo Verginelli died. On November 12, 2014, Dr...

Mahmut Şevket Paşa Osmanlı Sadrazamı ve Harbiye Nazırıdır. Tarih içerisinde hem askeri de siyasi yönden birçok eleştirilere maruz kalmıştır. Askeri açıdan Arnavut isyanları sırasında ki sert tavrı, Trablusgarp Balkan Savaşları aldığı kararlar, ise İttihat Terakki Fırkası ile ilişkileri tartışılmıştır. Onun meclis mebuslar üzerinde baskın bir kişiliği vardır. Fırkasına yakın tavrı nedeniyle İtti...

We introduce a new computational approach for femtosecond pulse propagation in the transparency region of gases that permits full resolution in three space dimensions plus time while fully incorporating quantum coherent effects such as high-harmonic generation and strong-field ionization in a holistic fashion. This is achieved by utilizing a onedimensional model atom with a delta-function poten...

In theory, there are analogous transformations of light’s spin and orbital angular momentum [Allen and Padgett, J. Mod. Opt. 54, 487 (2007)]; however, none have been observed experimentally yet. In particular, it is unknown if there exists for the orbital angular momentum of light an effect analogous to the spin angular momentum-based optical rotation; this would manifest itself as a rotation o...

A new viscometric technique, capable of detecting DNA strand breaks and alkali-labile sites by monitoring time-dependent changes of DNAreduced viscosity, has been used to analyze dose-response curves for the induction of DNA damage in liver of rats treated with single p.o. doses of sixteen A-nit roso compounds. Statistically significant changes of DNA viscometric parameters, which are considere...