Persistent facial swelling may occur as a rare complication of rosacea. This finding has been referred to as lymphedematous rosacea, Morbihan's disease or persistent solid facial edema. A literature review for cases of lymphedematous rosacea revealed that the chronic inflammatory process that accompanies the disease contributes to an increase in the permeability of blood vessels. With time, the...

Oral azithromycin has been used successfully to treat rosacea, a chronic skin disease that requires long-term therapy. A study was undertaken to determine if C. pneumoniae could play a causative role in acne rosacea. A series of 10 adults presenting with acne rosacea were selected to receive azithromycin alone for the treatment of acne rosacea. C. pneumoniae was detected in cheek biopsy specime...

OBJECTIVE To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. SUBJECTS AND METHOD Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia, between September 2011 and September 2012 and 20 age- and sex-matched control patien...

BACKGROUND There is no appropriate and reliable method of evaluating and monitoring severity in rosacea. OBJECTIVE To determine the importance of nailfold capillaroscopy as a diagnostic and prognostic method for patients with rosacea. METHODS A cross-sectional study where eight patients with rosacea and 8 control subjects were submitted to nailfold capillaroscopy from May to July 2009. We c...

OBJECTIVE To examine clinical associations, family history of rosacea, and response to treatment in prepubertal children with steroid rosacea. DESIGN Retrospective case-series evaluation of children younger than 13 years with steroid rosacea seen over an 8-year period (1991-1998). SETTING Ambulatory care university hospital. PATIENTS Referral patients from pediatricians serving a populati...

BACKGROUND There is an unmet need for general population-based epidemiological data on rosacea based on contemporary diagnostic criteria and validated population survey methodology. OBJECTIVE To evaluate the prevalence of rosacea in the general population of Germany and Russia. METHODS General population screening was conducted in 9-10 cities per country to ensure adequate geographic repres...

BACKGROUND Rosacea is a chronic skin disorder that adversely affects patients' quality of life. Current studies focus on the therapies that treat the clinical signs and symptoms of rosacea, but the impact of this disease on patients' emotional health and quality of life is often overlooked. OBJECTIVES To describe the disease burden of rosacea and the psychosocial implications on patients' qua...

A Glycomics approach to detect disease is illustrated in the analyses of human tear fluid for rosacea. The diagnosis of ocular rosacea is particularly challenging in a subgroup of patients that do not present with typical facial skin findings but have ocular signs and symptoms. Indeed, up to 90% of patients with ocular rosacea may have neither obvious roseatic skin changes nor a previous diagno...

Hypothyroidism is a common disease, and there may be a link between hypothyroidism and inflammatory skin disease. The purpose of this study is to assess whether hypothyroidism is more prevalent in psoriasis or rosacea patients. We utilized a large claims-based database to analyze rates of hypothyroidism in patients with psoriasis and rosacea compared to other patients with skin diseases. Partic...

Rosacea is a very common skin disorder in the clinical practice that primarily affects the convex areas of the face. Extrafacial rosacea lesions have occasionally been described, but extensive involvement is exceptional. In the absence of its typical clinical or histological features, the diagnosis of extrafacial rosacea may be problematic. We describe an unusual case of rosacea with very exube...