background: root canal cleaning is an important step in endodontic therapy. in order to develop better techniques, a new generation of endodontic instruments has been designed. the aim of this study was to compare the effectiveness of manual k-files (mani co, tokyo, japan) and two rotary systems–mtwo (dentsply-maillefer, ballaigues, switzerland) and protaper (vdw, munich, germany)–for root cana...