Phosphorylation of photoactivated rhodopsin by rhodopsin kinase (RK or GRK1), a first step of the phototransduction cascade turnoff, is under the control of Ca(2+)/recoverin. Here, we demonstrate that calmodulin, a ubiquitous Ca(2+)-sensor, can inhibit RK, though less effectively than recoverin does. We have utilized the surface plasmon resonance technology to map the calmodulin binding site in...

In this paper an adaptable algorithm for simulating CNN arrays is implemented using various RK-fourth order means such as Arithmetic Mean [AM], Centroidal Mean [CM], Harmonic Mean [HM], Contra Harmonic Mean [CoM], Heronian Mean [HeM], Geometric Mean [GM] and Root Mean Square [RMS] also, it is compared with RK-fourth order embedded means such as the RK-Embedded Heronian Mean, RK-Embedded Centroi...

The Epstein-Barr virus (EBV) BamHI A transcripts are a family of transcripts that are differentially spliced and can be detected in multiple EBV-associated malignancies. Several of the transcripts may encode proteins. One transcript of interest, RK-BARF0, is proposed to encode a 279-amino-acid protein with a possible endoplasmic reticulum-targeting sequence. In this study, the properties of RK-...

Form a random k-SAT formula on n variables by selecting uniformly and independently m = rn clauses out of all 2 ( n k ) possible k-clauses. The Satisfiability Threshold Conjecture asserts that for each k there exists a constant rk such that, as n tends to infinity, the probability that the formula is satisfiable tends to 1 if r < rk and to 0 if r > rk . It has long been known that 2/k < rk < 2....

PURPOSE To describe the presentation and clinical course of eyes with a history of radial keratotomy (RK) and varying degrees of endothelial degeneration. METHODS Retrospective case series were used. RESULTS Thirteen eyes (seven patients) were identified with clinical findings of significant guttata and a prior history of RK. The mean age of presentation for cornea evaluation was 54.3 years...

Upon illumination rhodopsin kinase (RK) phosphorylates the visual pigment, rhodopsin, in a reaction that is thought to terminate in part the biochemical events that follow photon absorption. In this paper, RK was studied to assign functional regions to the primary structure of the enzyme. Peptides derived from the sequence of RK were used to prepare site-specific anti-peptide antibodies against...

The Ramsey number rk(s, n) is the minimum N such that every red-blue coloring of the k-subsets of {1, . . . , N} contains a red set of size s or a blue set of size n, where a set is red (blue) if all of its k-subsets are red (blue). A k-uniform tight path of size s, denoted by Ps, is a set of s vertices v1 < · · · < vs in Z, and all s−k+1 edges of the form {vj , vj+1, . . . , vj+k−1}. Let rk(Ps...

Systems biology is an emerging field that aims at obtaining a system-level understanding of biological processes. The modelling and simulation of networks of biochemical reactions have great and promising application potential but require reliable kinetic data. In order to support the systems biology community with such data we have developed SABIO-RK (System for the Analysis of Biochemical Pat...

Streptomyces griseus and bacteriophage B were used for an assay system detecting anti-bacteriophage antibiotics. Streptomyces sp. RK-1441 was found to produce antibacteriophage antibiotics, RK-1441A and B, which are pyrrolo[1,4]benzodiazepine group antibiotics related to neothramycin. Both RK-1441A and B had antibacteriophage activity. The former showed antimicrobial activity on a hypersensitiv...

Let F be a free group (pro-p group) and U and W two finitely generated subgroups (closed subgroups) of F . The Strengthened Hanna Neumann conjecture says that ∑ x∈U\F/W rk(U ∩ xWx−1) ≤ rk(U)rk(W ), where rk(U) = max{rk(U)− 1, 0}. This conjecture was proved in the case of abstract groups independently by J. Friedman and I. Mineyev in 2011. In this paper we give the proof of the conjecture in the...