Autoimmune hemolytic anemia (AIHA) is a collective term for several diseases characterized by autoantibody-initiated destruction of red blood cells (RBCs). Exact subclassification is essential. We provide a review of the respective types of AIHA with emphasis on mechanisms of RBC destruction, focusing in particular on complement involvement. Complement activation plays a definitive but limited ...

The association between autoimmune hemolytic anemia (AIHA) and subsequent appearance of lymphoproliferative disorders (LPDs) has not been properly addressed in large-scale studies. We evaluated 107 patients with idiopathic (67 patients) or underlying (40 patients) immune disorders diagnosed with AIHA between 1992 and 1999. The following variables were examined in univariate and multivariate ana...

​A anemia hemolítica autoimune (AIHA) é uma doença incomum, em que ocorre a destruição de hemácias mediada por autoanticorpos do hospedeiro, sendo sua patogênese ainda pouco esclarecida. O presente estudo descreve um caso mulher 45 anos com idiopática clínica sugestiva mediação anticorpos quentes (w-AIHA) e laboratório confirmatório aglutinina fria (DAC). Observou-se história comum às anemias h...

OBJECTIVE To determine whether a narrower gauge needle used in ABG sampling is associated with lower pain scores and complication rates without increasing the level of difficulty of the procedure. METHODS We performed a prospective single-blinded randomised control study of patients from a tertiary-level emergency department in Sydney who required an ABG analysis over the period of June 2010-...

none of the available drugs are able to stop severe hemolysis immediately [4]. In view of these facts, each newly diagnosed ‘AIHA’ may become a challenging experience for the doctor who is responsible for the patient for several reasons: i) There is no close relationship between the laboratory findings and the clinical symptoms of the patient. ii) Hypoxic anemia may require urgent transfusion. ...

INTRODUCTION Unlike autoimmune hemolytic anemia (AIHA), literature on the etiological study of non-autoimmune hemolytic anemia (non-AIHA) is scarce. The incidence and prevalence of non-AIHA in different geographic regions are largely unknown perhaps owing to the lack of perspective investigation and different profiles of etiologies from different geographic regions. We aimed to examine the real...

The association between primary biliary cirrhosis (PBC) and autoimmune hemolytic anemia (AIHA) is uncommon; only fourteen such case reports have been described. In this report, three patients who developed AIHA on the basis of PBC underwent successful therapy with corticosteroids and ursodeoxycholic acid (UDCA). Patient 3 was more complicated, suffering from PBC, Evans syndrome, Sjögren syndrom...

autoimmune haemolytic anaemia (aiHa) is a rare disease. in clinical practice, diagnosis and treatment of aiHa turns out to be troublesome. Correct diagnosis is dependent on proper comprehension of the pathophysiology and the laboratory tests performed by the transfusion laboratory. the present review provides a short overview on the pathogenesis of autoimmune haemolytic anaemia. the diagnostic ...

Autoimmune hemolytic anemia (AIHA) is rarely seen in Hodgkin lymphoma (HL) patients, with a reported incidence of 0.2–4.2%.1-3 Sporadic case reports and reviews have shown that when AIHA occurs in HL patients, it happens mostly at stages III and IV of nodular sclerosis HL (NSHL) or mixed cellularity HL (MCHL).4 We present a case of AIHA at the time of diagnosis of classic HL, stage IIIB, with a...

We describe a new technique for removing a large intraocular foreign body by 25-gauge microincision vitrectomy surgery (25G-MIVS). Noncomparative interventional case series were performed at a single centre. Two patients with a long smooth intraocular vitreal foreign body underwent phacoemulsification and aspiration, intraocular lens implantation, 25G-MIVS, and extraction of the foreign body. T...