Tuberous sclerosis or tuberous sclerosis complex (TSC) is an autosomal dominant inherited disease characterized by the triad epilepsy, hamartomas (angiofibroma) and reduced intellectual capacity. Phenotype can vary considerably. Almost all patients with TSC have at least one characteristic dermatologic feature. Facial angiofibroma can cause severe disfigurement. It may involve the cheeks, perio...

Rhinophyma is a benign and disfiguring tumor of the nose, affecting white old men. It represents the end stage of acne rosacea. Hypertrophy of the sebaceous apparatus and fibrosis lead to an enlarged, erythematous nasal tip with comedones. Treatment modalities include Isotretinoin (Which is not effective on severe rhinophyma), freehand scalpel shave, cryosurgery, electrocautery, dermabras...