The Rh blood group antigens derive from 2 genes, RHD and RHCE, that are located at chromosomal position 1p34.1-1p36 (chromosome 1, short arm, region 3, band 4, subband 1, through band 6). In whites, a cde haplotype with a deletion of the whole RHD gene occurs with a frequency of approximately 40%. The relative position of the 2 RH genes and the location of the RHD deletion was previously unknow...

It is thought that the Rh antigens may be important in maintaining normal erythrocyte membrane integrity. Despite their name, Rh antigens are serologically present only on human erythrocytes. Rh structural polymorphisms are known to reside within a family of nonglycosylated Mr 32,000 integral membrane proteins that can be purified by hydroxylapatite chromatography. Mr 32,000 integral membrane p...

Background: RhD antigen system is the leading cause of hemolytic disease of the fetus and newborn (HDFN). Paternal molecular RhD zygosity test is valuable to decide on the use of anti-D immunoglobulin prophylaxis in Rh D-negative pregnant women. We aimed to investigate the paternal RhD zygosity by two molecular methods among blood donors in Kurdistan province, the west of Iran. We also compared...

Frequency of Rhesus and ABO blood groups was determined in 3012 mothers. The blood groups in order of frequency were B, O, A and AB. Only 6.2% mothers were rhesus negative. ABO haemolytie disease of the newborn (HDN) accounted for 15.7% and Rh-HDN for 12.7% of 306 neonate admitted with Jaundice. No significant difference was found in two groups when levels of serum bilirubin, exchange transfusi...

Background: ABO blood group antigens may play a role in the pathophysiology of certain diseases. Several studies have investigated the relation between blood group and autoimmune disorders. In this research, we evaluated the associations between ABO blood types and rhesus (Rh) factor in pemphigus patients.Methods: In this case-control, hospital-based study, we evaluated the prevalence of blood ...

Background: The Rhesus-D negative blood group is not as common in Africans when compared to Caucasians thus the need optimize surgical patients prior procedures. Blood “O” Rh-D a universal donor hence its importance emergency situations where there no time type and cross match blood.This because may transfusion pre-operatively, intra-operatively or post-operatively. Aim: To determine prevalence...

Human red blood corpuscles contain many antigens besides the A and B factors, those of greatest clinical importance being the Rb factors. The first of these factors was discovered by Landsteiner and Wiener (1940), and was so called because a similar factor is present in the corpuscles of the Rhesus monkey. This factor is demonstrable in the corpuscles of 85 per cent, of Europeans an^ white Amer...

The correlation between ABO/Rh blood groups and diabetes mellitus is still controversial. The aim of this study was to determine the relationship between ABO/Rhesus blood groups and diabetes in Turkish population. This cross-sectional study was conducted in Istanbul Medeniyet University Göztepe Education and Training Hospital's Diabetes Units. The study group was composed of 421 patients with t...

OBJECTIVE To assess the Rhesus (Rh) and Kell (K) phenotype of voluntary blood donors and lay foundation of a data bank of voluntary blood donors. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Blood Bank, The Aga Khan University Hospital, Karachi, in the year 2014. METHODOLOGY Voluntary blood donors were inducted after taking written informed consent. Three -5cc of EDTA a...