The treatment of patients with coronary artery disease continues to evolve, including those presenting with stable angina pectoris as well as those presenting with acute coronary syndromes. Pharmacological treatments which have changed practice in recent years include statins, angiotensin converting enzyme inhibitors, clopidogrel, and glycoprotein IIb/IIIa inhibitors. There have been major chan...

Chronic mesenteric ischaemia is a rare and potentially fatal condition most commonly due to atherosclerotic stenosis or occlusion of two or more mesenteric arteries. Multivessel revascularisation of both primary mesenteric vessels, the celiac artery and superior mesenteric artery (SMA), is the current mainstay of treatment; however, in a certain cohort of patients, revascularisation one or both...

The treatment of patients with coronary artery disease continues to evolve, including those presenting with stable angina pectoris as well as those presenting with acute coronary syndromes. Pharmacological treatments which have changed practice in recent years include statins, angiotensin converting enzyme inhibitors, clopidogrel, and glycoprotein IIb/IIIa inhibitors. There have been major chan...

BACKGROUND Stenosis of the internal carotid artery has been associated with cognitive impairment and decline. However, studies testing the effect of carotid revascularisation on cognition have had conflicting results. This may in part be explained by variation in the flow territory of the carotid artery. In 12 to 36% of the patients, the posterior cerebral artery is mainly or exclusively suppli...

OBJECTIVES To review the results of surgical revascularisation for left main coronary artery stenosis and the associated vascular pathology that is responsible for cerebrovascular complication. PATIENTS 60 patients (45 men, 15 women) (mean age 61.3 (39-79)) who underwent revascularisation for stenosis of the left main stem coronary artery (LMS) between January 1987 and August 1990 were compar...

INTRODUCTION The bioresorbable vascular scaffold system (BVS) is the latest fully absorbable vascular therapy system that is used to treat coronary artery disease. The BVS has been used in different coronary lesion subsets, such as acute thrombotic lesions, bifurcation lesions, ostial lesions and lesions originating from bypass grafts. However, data about the use of BVS in chronic total occlusi...

OBJECTIVE To assess whether revascularisation that is considered to be clinically appropriate is also cost effective. DESIGN Prospective observational study comparing cost effectiveness of coronary artery bypass grafting, percutaneous coronary intervention, or medical management within groups of patients rated as appropriate for revascularisation. SETTING Three tertiary care centres in Lond...

Objectives This is a protocol for Cochrane Review (intervention). The objectives are as follows: To analyse the effects of supervised exercise programme following successful lower limb revascularisation compared with standard care in patients symptomatic peripheral artery disease (PAD).