OBJECTIVE To examine select adipokines, including fatty acid-binding protein 4, retinol-binding protein 4, and high-molecular-weight (HMW) adiponectin in relation to cardiovascular disease (CVD) mortality among patients with type 2 diabetes mellitus. APPROACH AND RESULTS Plasma levels of fatty acid-binding protein 4, retinol-binding protein 4, and HMW adiponectin were measured in 950 men with...

Retinol-binding protein 4(RBP4), and irisin originally described as an adipocyte-specific hormone, has been suggested to be important link between obesity, insulin resistance diabetes. To test the hypothesis that RBP4, concentrations will higher in obese subject than normal weight. A total of 176 individuals were evaluated, which divided into three groups according BMI. Group I (Normal Weight g...

High vitamin A ingestion or high serum retinol have been postulated to increase the risk of fractures and osteoporosis by reduced bone mineral density (BMD). Retinol is carried and transported to the tissues bound to retinol binding protein 4 (RBP4) and transthyretin (TTR). The relationships between retinol, retinol transport protein, retinol binding protein 4 (RBP4) and transthyretin (TTR) and...