The purpose of this study was to investigate the peripapillary retinal nerve fiber layer (RNFL) thickness in myopic, emmetropic, and hyperopic children using optical coherence tomography. Two-hundred one right eyes of subjects aged 4 to 18 years were divided into 3 groups based on their postcycloplegic spherical equivalent: myopes (< 1.0 D), emmetropes ( 1.0 to þ1.0 D), and hyperopes (>þ1.0 D)....

OBJECTIVE To assess optical coherence tomography in differentiating optic disc edema (ODE) due to papilledema and other optic neuropathies from optic nerve head drusen (ONHD). METHODS Optical coherence tomographic images from 60 subjects (20 with ODE, 20 with ONHD, and 20 control subjects) were assessed qualitatively and quantitatively. Qualitative criteria for ODE included an elevated optic ...

AIMS To compare histological thickness of the retinal nerve fibre layer in the primate with retardation measurements obtained in vivo using the Mark II Nerve Fiber Analyzer (NFA, Laser Diagnostic Technologies, San Diego, USA). METHODS Scanning laser polarimetry was performed on both eyes of a healthy anaesthetised adult primate (Macaca mulatta). The retinal nerve fibre layer thickness was mea...

The neural capacity (NC) of high-pass resolution perimetry (HRP) was compared to the retinal nerve fiber layer thickness measured with the GDx Nerve Fiber Analyzer in 74 patients with either ocular hypertension or primary open-angle glaucoma at various stages of severity. A statistically significant correlation was found between the NC and the GDx ellipse average, the total polar integral, and ...

In this study, optical coherence tomography (OCT) was used to evaluate retinal thickness in two patients with optic neuropathy who had recently discontinued ethambutol. OCT was used to measure retinal nerve fiber layer (RNFL) thickness and to map the RNFL, ganglion cell layer (GCL), and inner plexiform layer (IPL). Decreased RNFL thickness was observed in one case. However, the combined RNFL, G...

Introduction: We investigated correlation between the retinal nerve fiber layer (RNFL) thickness and the severity of Parkinson's disease (PD). Methods: In this study, the RNFL thickness of 23 patients with Parkinson’s disease (PD) was compared to normal controls (NCs). PD severity was assessed by the MDS-UPDRS (movement disorder society Unified Parkinson Disea...

PURPOSE To determine the effects of X-linked and autosomal recessive Alport syndrome on retinal basement membranes and how these result in the characteristic perimacular dot-and-fleck retinopathy, lozenge, and macular hole. METHODS The type IV collagen chains present in the normal retina were determined immunohistochemically. Ten patients with Alport syndrome underwent retinal photography and...