Heart disease is the leading cause of death. Each year in the United States, more than 500,000 men and women die from coronary artery disease (CAD). CAD results from the narrowing of blood vessels that supply the heart. The blood vessels become narrow when fatty deposits build up inside the arterial wall. When the arteries become clogged, the blood flow to the myocardium is impaired and a heart...

BACKGROUND Attenuation correction (AC) improves the diagnostic outcome of stress-only myocardial perfusion imaging (MPI) using conventional SPECT. Our aim was to determine the value of AC using a cadmium zinc telluride-based (CZT)-SPECT camera. METHODS AND RESULTS We retrospectively included 107 consecutive patients who underwent stress-optional rest MPI CZT-SPECT/CT. Next, we created three t...

BACKGROUND Stress nuclear myocardial perfusion imaging (MPI) is an established method for diagnosis and prognosis of coronary artery disease (CAD). However, radiation exposure limits its clinical application. Magnetocardiography (MCG) has been proposed as a non-contact, rapid and non-radiation technique with high reproducibility. The aim of the study was to evaluate the diagnostic efficacy of r...

BACKGROUND Myocardial perfusion imaging (MPI), using single photon emission computed tomography (SPECT) is a validated method for detecting coronary artery disease. Transthoracic Doppler echocardiography (TTDE) of flow at rest and during adenosine provocation has previously been evaluated in selected patient groups. We therefore wanted to compare the diagnostic ability of TTDE in the left anter...

UNLABELLED A triple-detector, multipinhole SPECT system was optimally configured to perform simultaneous (201)Tl (stress)/(99m)Tc (rest) myocardial perfusion imaging (MPI) using a protocol that permitted direct diagnostic comparison of this multipinhole SPECT system with conventional rotational SPECT. METHODS Both the rotational and the multipinhole SPECT systems used the same model gamma-det...

On the basis of some new evidences in favor of delayed (99m)Tc methoxy-isobutyl-isonitrile ((99m)Tc-MIBI) redistribution, doubts about the appropriate time of acquisition following radiotracer injection may be raised. The goal of this study was to find the best acquisition time at stress and rest phases to achieve the highest sensitivity and normalcy rate for (99m)Tc-MIBI SPECT. Ninety four pat...

Abstract Background False negative myocardial perfusion images on single-photon emission computed tomography (SPECT) imaging (MPI) is a substantial problem in the interpretation of MPI. To explore possible parameters from gated SPECT that could detected coronary artery disease (CAD) patients with normal images, we retrospectively selected who underwent 2-day Tc-99 m MIBI adenosine stress/rest M...

  Objective: IQSPECT is an advanced high-speed SPECT modality for performing myocardial perfusion imaging (MPI), which uses a multi-focus fan beam collimator with resolution recovery reconstruction. The aim of this study was to compare IQSPECT compared with conventional SPECT interms of performance based on standard clinical protocols. In addition, we examined the concordance between convention...

Introduction: The main purpose of this study was to compare transient ischemic dilation (TID) ratios in SPECT-low dose CT and SPECT Myocardial Perfusion Imaging (MPI) by application of different quantitative programs and quantify the possible shift in the upper normal limits of TID ratio in the SPECT-CT MPI. Methods: 149 Patients with low pre-test probability for coronary artery disease (CAD), ...

OBJECTIVE While nuclear myocardial perfusion imaging (MPI) offers many benefits to patients with known or suspected cardiovascular disease, concerns exist regarding radiation-associated health effects. Little is known regarding MPI practice in Africa. We sought to characterise radiation doses and the use of MPI best practices that could minimise radiation in African nuclear cardiology laborator...