A simple and sensitive technique for detection of reverse transcriptase (RT) activity in real time has been developed. The technique is based on continuous detection of the inorganic pyrophosphate formed in the RT-catalyzed reaction by a luminometric method. The technique has been used for continuous monitoring of RT-catalyzed DNA synthesis on both homo- and heteropolymeric templates. The assay...

Background: Tumor response after multimodality treatment using combination of radiation, chemotherapeutic drugs and hyperthermia usually assessed by parameters such as tumor growth delay, volume doubling time and regression response. The study herein was conducted to investigate the usefulness of micronucleus assay for assessing the multimodality treatment. Materials and Methods: The ...

background: tumor response after multimodality treatment using combination of radiation, chemotherapeutic drugs and hyperthermia usually assessed by parameters such as tumor growth delay, volume doubling time and regression response. the study herein was conducted to investigate the usefulness of micronucleus assay for assessing the multimodality treatment. materials and methods: the induction ...

This paper proposes an integrated modelling approach for location planning of radiotherapy treatment services based on cancer incidence and road network-based accessibility. Previous research efforts have established travel distance/time barriers as a key factor affecting access to cancer treatment services, as well as epidemiological studies have shown that cancer incidence rates vary with pop...

Flash radiotherapy (Flash-RT) is an innovative technique used in for cancer treatment because it delivers extremely high dose of radiation (>40 Gy/s) to the tumour a very short period time, typically within fraction second. This ultra-fast delivery distinguishes Flash-RT from conventional radiotherapy, which involves over longer time period, often several minutes. Studies conducted cell and ...

OBJECTIVES This research's main goals were to build a predictor for a turnaround time (TAT) indicator for estimating its values and use a numerical clustering technique for finding possible causes of undesirable TAT values. MATERIALS AND METHODS The following stages were used: domain understanding, data characterisation and sample reduction and insight characterisation. Building the TAT indic...

In recent years, the FlexRay communication protocol has been promoted as a de facto standard for in-vehicular communications. In the FlexRay protocol, the communication timeline is organized as a sequence of four segments, whereas the static segment defines a set of slots specifically designed for the transmission of synchronous messages. In this paper, we investigate the following problem: "ho...