results nearly 60% of the responders had witnessed more than two emergencies in the previous six months and 55% had actively participated in helping the injured person. the nature of the help was mainly by calling for an ambulance (41.5%), transporting the injured (19.7%) and consoling the victim (14.9%). majority (78.1%) of the responders informed that they had run to the victim (42.4%) or had...

the microdose gnrh agonist (gnrh-a) flare protocol may have a particular value for previously poor responders in whom it has been observed to stimulate dramatic increases in serum fsh. the purpose of this study was to determine the effects of microdose gnrh-a in poor responders. this is a clinical trial with before and after design. this study was done in research and clinical center for infert...

background: despite extensive progress in ivf techniques, one of the most difficult problems is the variability in the response to controlled ovarian hyperstimulation (coh). recent studies show the effects of individual genetic variability on coh outcome. objective: to evaluate the correlation between lhβ g1502a polymorphisms in exon 3 of the lh gene and ovarian response to coh. materials and m...

background: despite the impressive results obtained with imatinib, inadequate response or resistance are observed in certain patients. it is known that imatinib is a substrate of a multidrug resistance gene (mdr1). thus, interindividual genetic differences linked to single nucleotide polymorphisms in mdr1 may influence the metabolism of imatinib. the present study has aimed to examine the impac...

Background: Different studies have demonstrated that a small proportion of healthy individuals receiving the hepatitis B (HB) vaccine do not produce protective levels of anti-HB antibody, a phenomenon which could be linked to certain human leukocyte an-tigen (HLA) class-II alleles or haplotypes. Objectives: The present study was under-taken to determine the frequency of HLA class-II alleles in ...

Background Methadone therapy is a major protocol in opioid addiction cases in many health care systems. Population-based studies have shown that in addicted people, the genetic profile affects their response to methadone therapy. Therefore, this study designed to examine the frequency of two SNPs of the CYP2B6 gene (rs3745274 and rs3211371) in addicted cases in two methadone-responders and meth...

background: anti-mullerian hormone (amh) is constantly secreted during menstrual cycles and may offer several advantages over traditional biomarkers of ovarian reserve. objective: to assess the relationship of anti-mullerian hormone (amh) values, which are used to evaluate ovary reserves, with oocyte and embryo quality and with art outcomes in patients undergoing intra-cytoplasmic sperm injecti...