نتایج جستجو برای: respectively three different genotypic variants including aa

تعداد نتایج: 3886708  

2011
Max Doerfel Otmar Huber

In mammals, 7 distinct genes encoding CK1 isoforms (CK1 alpha, CK1 beta, CK1 gamma1, CK1 gamma2, CK1 gamma3, CK1 delta and CK1 epsilon) are expressed which differ mainly in length and primary structure of the C-terminal non-catalytic domain. Furthermore, CK1 alpha splice variants have been detected in many different organisms including vertebrates and mammals. Alternative splicing leads to the ...

2012
Ajit Kumar Saxena S. Pandey L. K. Pandey

In humans, neural tube failure to close during the 4th week of gestation leads to the development of severe congenital malformations of the central nervous system because of an error in maternal folate metabolism associated gene variants. The frequency of genotypic variants of GCP II (H475Y) and folate carrier RFCI (SLC19A1) gene polymorphism (80 G →A) were evaluated as potential candidate gene...

2013
Farzian Aminuddin Tillie-Louise Hackett Dorota Stefanowicz Aabida Saferali Peter D Paré Amund Gulsvik Per Bakke Michael H Cho Augusto Litonjua David A Lomas Wayne H Anderson Terri H Beaty Edwin K Silverman Andrew J Sandford

BACKGROUND Due to the pleiotropic effects of nitric oxide (NO) within the lungs, it is likely that NO is a significant factor in the pathogenesis of chronic obstructive pulmonary disease (COPD). The aim of this study was to test for association between single nucleotide polymorphisms (SNPs) in three NO synthase (NOS) genes and lung function, as well as to examine gene expression and protein lev...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Sophie Steeland Steven Timmermans Sara Van Ryckeghem Paco Hulpiau Yvan Saeys Marc Van Montagu Roosmarijn E Vandenbroucke Claude Libert

Genetic polymorphisms in coding genes play an important role when using mouse inbred strains as research models. They have been shown to influence research results, explain phenotypical differences between inbred strains, and increase the amount of interesting gene variants present in the many available inbred lines. SPRET/Ei is an inbred strain derived from Mus spretus that has ∼1% sequence di...

ژورنال: پژوهش در پزشکی 2012
ابراهیمی دریانی, ناصر, بالایی, هدیه, حبیبی, منیژه, زالی, محمد رضا, زجاجی, همایون, شریفیان, افسانه, فرنود, آلما, نادری, نصرت اله,

Abstract Background: NOD2 gene located on chromosome 16 (IBD1) is known to have a strong association with Crohn’s disease. Three common polymorphisms of this gene including R702W, G908R, 1007fsinsC, were reported to be frequent in many western populations while rare occurrence of them was observed in eastern countries. The aim of this study was to assess the frequency of these polymorphisms ...

Journal: :Genetics and molecular research : GMR 2010
L F B Pinto J B S Ferraz F V Meirelles J P Eler F M Rezende M E Carvalho H B Almeida R C G Silva

We examined whether single-nucleotide polymorphisms (SNPs) in the calpain (CAPN) and calpastatin (CAST) genes, described from Bos primigenius taurus, are polymorphic in Nellore cattle. We also looked for a possible association of linkage disequilibrium of this polymorphism with tenderness of the longissimus dorsi muscle after 7, 14 and 21 days of postmortem aging in 638 purebred Nellore bulls. ...

2017
Marie V Coignet Gary Robert Zirpoli Michelle R Roberts Thaer Khoury Elisa V Bandera Qianqian Zhu Song Yao

Reproductive aging phenotypes, including age at menarche (AM) and age at natural menopause (ANM), are well-established risk factors for breast cancer. In recent years, many genetic variants have been identified in association with AM and ANM in genome-wide association studies among European populations. Using data from the Women's Circle of Health Study (WCHS) of 1,307 European-American (EA) an...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه کاشان - دانشکده علوم انسانی 1390

increasing academic and professional language demands around the world are not a deniable fact. the purpose of this study was to investigate english language needs and communication needs of the chemistry students at master and ph.d. levels at the iranian universities. in this research, different methods were used including un-structured interview, structured interview, and two sets of question...

2016
Soo-Yon Rhee Kris Sankaran Vici Varghese Mark A. Winters Christopher B. Hurt Joseph J. Eron Neil Parkin Susan P. Holmes Mark Holodniy Robert W. Shafer

UNLABELLED HIV-1 protease (PR), reverse transcriptase (RT), and integrase (IN) variability presents a challenge to laboratories performing genotypic resistance testing. This challenge will grow with increased sequencing of samples enriched for proviral DNA such as dried blood spots and increased use of next-generation sequencing (NGS) to detect low-abundance HIV-1 variants. We analyzed PR and R...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت دبیر شهید رجایی - دانشکده علوم انسانی و پایه 1390

the present study aimed at investigating the relationship between iranian efl teachers’ classroom management orientations and their teaching styles. additionally, the difference between male and female teachers’ teaching styles and classroom management orientations and their relationship with experience and age were explored. three hundred efl teachers filled in attitudes and beliefs on classro...

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