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background : republic of azerbaijan is considered as an area with high prevalence of multi-drug resistant tuberculosis. uncontrolled travelling of azerbaijanis people to iran is the issue that needs to be considered as an important issue. methods : this study was conducted on 32 patients with tuberculosis from baku–nakhchivan and 48 patients from iran during 2012 to 2014. colonies of mycobacter...

Tuberculosis (TB) is a disease of worldwide public-health concern. The development of resistance to an increasing number of second-line drugs and those used to treat multidrug-resistant (MDR) TB is rapidly becoming an emergency that could hinder the prevention and treatment of TB globally. This study describes the resistance profile of MDR and extensively drug-resistant (XDR) TB with a hospital...

Emergence of drug resistant tuberculosis like multi drug resistant tuberculosis (MDR-TB), extensively drug-resistant tuberculosis (XDR-TB) and totally drug resistant tuberculosis (TDR-TB) has created a new challenge to fight against these bad bugs of Mycobacterium tuberculosis. Repurposing and revival of the drugs are the new trends/options to combat these worsen situations of tuberculosis in t...

In this paper, we present a mathematical model for the study of resistance to tuberculosis treatment using fractional derivatives in Caputo sense. This takes into account relationship between Tuberculosis, HIV/AIDS, and diabetes differentiates cases MDR-TB (multidrug-resistant tuberculosis) XDR-TB (extensively drug-resistant tuberculosis). We basic results associated with behavior disease-free ...

objective(s) isoniazid (inh) is one of the main first line drugs used in treatment of tuberculosis and development of resistance against this compound can result in serious problems in treatment procedures. resistance to inh is mediated mainly by mutation in katg gene that is coded for the catalase enzyme. the proportional method for detection of inh-resistance is time consuming due to the slow...

in this study, twenty-five strains of mycobacterium tuberculosis resistant to isoniazid (inh) were isolated from patients with tuberculosis (tb). nine strains (36%) were found to be virulent in guinea-pigs [root index virulence (riv» 1 ]. the remaining sixteen strains (64%) were non-virulent (riv <1). of the nine strains resistant to inh as well as virulent to guinea-pigs, eight of them were fo...

Drug-resistant tuberculosis, in particular Multi-Drug Resistant (MDR-TB) is an increasing global concern and a major burden for some developing countries, especially the BRICS. It is assumed that every year roughly 350 000 new MDR-TB cases occur in the world, on average in 20.5% of TB patients that have been previously treated but also in 3.5% of persons that have never been on TB treatment bef...

Peng et al.[1] reported that the MDR‐TB burden among the new tuberculosis (TB) patients accounted for more than 1/4th of all multidrug‐resistant TB (MDR‐TB) cases in the past 5 years in Zhejiang province, although the identified rate of MDR‐TB among 9830 new TB cases was only 2.0%. Drug‐resistant TB, especially MDR‐TB, is a major threat to the control of TB worldwide. However, due to high cost ...