Neuropeptide Y (NPY) is a cotransmitter with norepinephrine (NE) and ATP in sympathetic nerves. There is evidence for increased activity of the sympathetic nervous system and the renin-angiotensin system (RAS), as well as a role for NPY in the development of hypertension in experimental animal models and in humans. Angiotensin II (ANG II) is known to facilitate sympathetic neurotransmission, an...

The present study was undertaken to look for the effect of chloroethylclonidine (CEC) on prejunctional alpha-2 autoreceptors of the canine saphenous vein. The effect was tested on tritium overflow evoked by electrical stimulation from tissues preloaded with 0.2 microM 3H-norepinephrine. Yohimbine (3-300 nM) and CEC (1-125 microM) increased and UK-14,304 reduced the overflow of tritium evoked by...

Motor overflow is extraneous movement in a limb not involved in a motor action. Typically, overflow is observed in people with neurological impairments and in healthy children and adults during strenuous and attention-demanding tasks. In the current study, we found that young infants produce vast amounts of motor overflow, corroborating claims of symmetry being the default state of the motor sy...

Multiple motor abnormalities have been identified in some children with Attention Deficit/Hyperactivity Disorder (ADHD). These include persistence of overflow movements, impaired timing of motor responses and deficits in fine motor abilities. Motor overflow is defined as co-movement of body parts not specifically needed to efficiently complete a task. The presence of age-inappropriate overflow ...

Overflow occurs when a value is represented in binary using an insufficient number of bits. Values that lie outside the bit range are misinterpreted as values within the bit range. Continuous signals that suffer from integer overflow can be correcting using unwrap functions, but this correction fails when significant noise is present. A new method of correcting signals is proposed which uses mo...

Many studies have considered the effects of suspension properties on the dewatering process but fewhave focused on ore properties. Thus, the present work studied the effects of ore properties (density,particle size, mineralogy) on the dewatering process based on lab and pilot experiments. A hydrocyclonewas used to prepare the required samples for the experiments. To study the effects of mineral...

The effect of ischemia on cholinergic presynaptic inhibition of exocytotic norepinephrine release was studied in the innervated perfused rat heart. In normoxic hearts, vagal nerve stimulation significantly reduced exocytotic norepinephrine overflow to 75% of control values. This inhibitory effect was not affected by 3 minutes of low-flow ischemia (67% of control overflow values), but was attenu...

The paper recommends new methods to estimate effectively the probabilities of buffer overflow in high-speed communication networks. The frequency of buffer overflow in queuing system is very small; therefore the overflow is defined as rare event and can be estimated using rare event simulation with continuous-time Markov chains. First, a two-node queuing system is considered and the buffer over...