Urinary tract infection (UTI) is a common bacterial illness in children. Acute pyelonephritis in children may lead to renal scarring with the risk of later hypertension, preeclampsia during pregnancy, proteinuria, and renal insufficiency. Until now, vesicoureteral reflux (VUR) has been considered the most important risk factor for post-UTI renal scar formation in children. VUR predisposes child...

Much of the confusion in the discussion of these topics reflects differences of nomenclature not of fact, and a failure to relate the wide variation in severity both of reflux and of renal damage to their long-term implications. In this article, significant bacteriuria denotes the presence of actively multiplying organisms in the urinary tract and is indicated in girls by a pure growth of at le...

A review of 105 children with urinary tract infection showed an increasing prevalence of grades II-III vesicoureteric reflux with diminishing age. During infancy reflux was almost always severe, and affected boys as often as girls. Radiologically scarred kidneys were drained by refluxing ureters in 98% of cases. The prevalence of scars also rose significantly with increasinglyly severe reflux. ...

Background: Pyelonephritis can lead to renal scar. Objective: To evaluate the effects of betamethasone in preventing renal scarring in rat model of pyelonephritis. Methods: Sixty three female Sprague-Dawley rats were divided into seven groups. Group A was the control. Mannose-sensitive E coli was directly inoculated into the left kidney exposed under general anesthesia in groups C–G. Group B re...

Moderate antenatal renal pelvic dilation (5-15 mm) may suggest vesicoureteric reflux, but it is not known to predict renal scarring. Dimercaptosuccinic acid scans on such children aged over 4 years showed a scarring rate (0/133 boys, 1/56 girls) similar to our local population. Investigation and treatment of moderate dilation may not be required.

Much of the confusion in the discussion of these topics reflects differences of nomenclature not of fact, and a failure to relate the wide variation in severity both of reflux and of renal damage to their long-term implications. In this article, significant bacteriuria denotes the presence of actively multiplying organisms in the urinary tract and is indicated in girls by a pure growth of at le...

Much of the confusion in the discussion of these topics reflects differences of nomenclature not of fact, and a failure to relate the wide variation in severity both of reflux and of renal damage to their long-term implications. In this article, significant bacteriuria denotes the presence of actively multiplying organisms in the urinary tract and is indicated in girls by a pure growth of at le...

BACKGROUND AND PURPOSE The aim was to identify the risk factors for renal scarring and deteriorating renal function in children with primary vesico-ureteral reflux (VUR). MATERIALS AND METHODS Patients with primary VUR admitted to the National Cheng Kung University Hospital were retrospectively analyzed. The outcomes were renal scarring, assessed by technetium-99 m dimercaptosuccinic acid sca...