We report a case of an isolated para-aortic retroperitoneal renal cell carcinoma (RCC) in the absence primary cancer kidney. Single reports literature have described extra-renal RCC different locations with no evidence tumor. present initial presentation, diagnostic imaging, surgical treatment, and pathologic evaluation. Immunohistochemistry demonstrated positivity for TFE3 TFEB, both which are...

Medical therapies are lacking for advanced renal cancer, so there is a great need to understand its pathogenesis. Most renal cancers have defects in the von Hippel-Lindau tumor suppressor pVHL. The mechanism by which pVHL protein functions in renal tumor suppression remains unclear. Jade-1 is a short-lived, kidney-enriched transcription factor that is stabilized by direct interaction with pVHL....

CONTEXT There is increasing evidence for the role of altered metabolism in the pathogenesis of renal cancer. OBJECTIVE This review characterizes the metabolic effects of genes and signaling pathways commonly implicated in renal cancer. EVIDENCE ACQUISITION A systematic review of the literature was performed using PubMed. The search strategy included the following terms: renal cancer, metabo...

OBJECTIVE Patients with end-stage renal disease are suggestive to have a higher risk for the development of some kinds of cancer. The aim of this study is to evaluate the possible association between malignancy and end-stage renal disease in Taiwan. METHODS We used the data of the National Health Insurance system of Taiwan to assess this issue. The end-stage renal disease cohort contained 21 ...

The incidence of renal cell cancer has been increasing worldwide. Although the incidence of renal cell cancer in Japan is lower than the rates in the other industrialized countries, there is no doubt that it is increasing. In this paper, we would like to introduce the result of our studies, which evaluate the risk factors for renal cell cancer in Japan. Hypertension, diabetes mellitus, kidney d...

cartilage hair hypoplasia (chh), is a rare cause of metaphyseal chondrodysplasia and short stature. other features included hair abnormality, immunodeficiency, anemia, gastrointestinal disorders (hirschsprung disease, celiac, …) and increased risk of cancer. the disease is an autosomal recessive disorder and previously has not been reported in iran. we report a 9-year-old boy diagnosed as carti...

Background: The aim of this study was to provide a novel approach for estimating the incidence of renal cancer in Germany by using hospitalization data from the years 2005–2006 and to compare these estimates with incidence rates from cancer registries. We used nationwide hospitalization data from the years 2005–2006 including 34.2 million hospitalizations. We used three definitions of potential...

BACKGROUND The aim of this study was to provide a novel approach for estimating the incidence of renal cancer in Germany by using hospitalization data from the years 2005-2006 and to compare these estimates with incidence rates from cancer registries. We used nationwide hospitalization data from the years 2005-2006 including 34.2 million hospitalizations. We used three definitions of potential ...

The authors conducted a population-based case-control study of 810 cases with histologically confirmed incident kidney cancer and 3,106 controls to assess the effect of obesity, energy intake, and recreational physical activity on renal cell and non-renal cell cancer risk in Canada from 1994 to 1997. Compared with normal body mass index (BMI; 18.5 to <25.0 kg/m2), obesity (BMI, >or=30.0 kg/m2) ...

background: renal cell carcinoma is the third most common urological cancer. surgical resection is still the mainstay of treatment for this tumor. here we present a new surgical approach for the management of locally advanced renal cell carcinoma. methods: we chose ten patients with extensive renal masses. the patient, under general anesthesia after preparation and draping, was placed in the su...