نتایج جستجو برای: remote ischemic

تعداد نتایج: 188808  

2015
Yufeng Zhai Lihua Ao Joseph C. Cleveland Qingchun Zeng T. Brett Reece David A. Fullerton Xianzhong Meng

UNLABELLED The signaling mechanism that mediates inflammatory responses in remote non-ischemic myocardium following regional ischemia/reperfusion (I/R) remains incompletely understood. Myocardial Toll-like receptor 4 (TLR4) can be activated by multiple proteins released from injured cells and plays a role in myocardial inflammation and injury expansion. We tested the hypothesis that TLR4 occupi...

2017
Zhenqiu He Nan Xu Sihua Qi

BACKGROUND Cognitive function impairment is one of the most common complications in elderly patients after surgery, and an ideal nonpharmacological therapy has not yet been identified. Thus, we hypothesized that remote ischemic preconditioning could improve cognitive functions in elderly patients after surgery and investigated the mechanism underlying this effect. METHODS Ninety patients clas...

2017
Amritpal Singh Aulakh Puneet Kaur Randhawa Nirmal Singh Amteshwar Singh Jaggi

Remote ischemic preconditioning (RIPC) is an intrinsic phenomenon whereby 3~4 consecutive ischemia-reperfusion cycles to a remote tissue (noncardiac) increases the tolerance of the myocardium to sustained ischemiareperfusion induced injury. Remote ischemic preconditioning induces the local release of chemical mediators which activate the sensory nerve endings to convey signals to the brain. The...

Journal: :Circulation 2012
Fikret Er Amir M Nia Henning Dopp Martin Hellmich Kristina M Dahlem Evren Caglayan Torsten Kubacki Thomas Benzing Erland Erdmann Volker Burst Natig Gassanov

BACKGROUND Contrast medium-induced acute kidney injury is associated with substantial morbidity and mortality. The underlying mechanism has been attributed in part to ischemic kidney injury. The aim of this randomized, double-blind, sham-controlled trial was to assess the impact of remote ischemic preconditioning on contrast medium-induced acute kidney injury. METHODS AND RESULTS Patients wit...

2013
Kristina Dupont

Stroke is a leading cause of death and disability worldwide. Intravenous administration of alteplase (rtPA) within 4.5 hours of symptom onset is currently the only approved drug treatment of acute ischemic stroke (AIS). Various forms of neuroprotection have proven effective in animal models of acute ischemia, but their translation into successful therapies in human stroke has so far been unsucc...

2015
Alberto Zangrillo Mario Musu Teresa Greco Ambra Licia Di Prima Andrea Matteazzi Valentina Testa Pasquale Nardelli Daniela Febres Fabrizio Monaco Maria Grazia Calabrò Jun Ma Gabriele Finco Giovanni Landoni Tobias Eckle

INTRODUCTION Cardioprotective properties of volatile agents and of remote ischemic preconditioning have survival effects in patients undergoing cardiac surgery. We performed a Bayesian network meta-analysis to confirm the beneficial effects of these strategies on survival in cardiac surgery, to evaluate which is the best strategy and if these strategies have additive or competitive effects. M...

Journal: :Annals of Clinical and Translational Neurology 2019

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