background: patients with graves’ disease exhibit a considerable rate of relapse after treatment with antithyroid drugs and require ablative therapy.   objective: the purpose of this study was to evaluate variables which can be used as prognostic factors in predicting the outcome of graves’ disease after treatment with antithyroid drugs.   methods: age, sex, duration of antithyroid drug therapy...

background: steroid dependent (sdns) and/or frequently relapsing idiopathic nephrotic syndrome (frins) is a therapeutic problem. this study was conducted to determine the effect of levamisole in children with steroid dependent and/or frequently relapsing nephrotic syndrome. methods: in this quasi-experimental study, 43 children aged 1-14 years with steroid dependent (23 cases) and/or frequently...

abstract background: leukemia is the most common malignancy in childhood, and acute myeloid leukemia (aml) is the second most common leukemia.aml still accounts for more than 30% of deaths from leukemia. aml is classified into several subgroups from m0 to m7 with different presentations, clinical features, and outcomes. material and methods: between march 1996 and october 2003, 47 children with...

OBJECTIVE Recently, the Remission in Schizophrenia Working Group proposed symptomatic remission criteria and pointed to the lack of data regarding functional remission and quality of life in schizophrenia. This post hoc analysis of data from German patients in the Schizophrenia Outpatient Health Outcomes study assessed rates and predictors of symptomatic and functional remission as well as adeq...

BACKGROUND There are few reports of the efficacy of adalimumab (ADA) for clinical remission and preventing postoperative recurrence in Crohn's disease (CD) in Asian real practice settings. We conducted a Japanese multicenter retrospective observational study. METHODS We evaluated patients with CD who were treated with ADA at 11 medical institutions in Japan to investigate the clinical efficac...

Estrogen receptors (ER's) were determined by agar gel electrophoresis in 105 human mammary tumor biopsies. Fifty-three tumor specimens revealed measurable amounts of receptor, and 64% of these patients showed an objective remission after endocrine treatment. If we also include cases with partial remission, previous response, and arrested growth but no actual remission, the benefit rate increase...

OBJECTIVE To examine the relationship between remission of psychiatric disorders and age. METHODS We interviewed 3258 randomly selected adult residents of Edmonton using the Diagnostic Interview Schedule (DIS), which yielded DIS/DSM-III diagnoses. Remission was defined as being free of symptoms of the index lifetime disorder in the year preceding the interview, this being the difference betwe...

PURPOSE Transsphenoidal surgery (TSS) is the primary treatment modality for Cushing's disease (CD). However, the predictors of post-operative remission and recurrence remain debatable. Thus, we studied the post-operative remission and long-term recurrence rates, as well as their respective predictive factors. METHODS A retrospective analysis of case records of 230 CD patients who underwent pr...

intensive induction therapy-in acute myeloid leukemia (aml), as in some other systemic malignancies- is a strategy fundamentally different from post-remission strategies. approaches like consolidation treatment, prolonged mainte nance, and autologous or allogeneic transplantation in the first remission are directed against minimal residual disease with a malignant cell population having survive...

BACKGROUND Although standard first line treatment of acute promyelocytic leukemia is All trans retinoic acid (ATRA) and chemotherapy, some patients relapse and need a second line of treatment. Relapsed cases of promyelocytic leukemia can be salvaged with arsenic trioxide. METHODS Between May 1999 and Jan. 2010, we treated 31 relapsed cases of promyelocytic leukemia with arsenic trioxide. Thes...