Label-free detection of the interaction between hexahistidine-tagged human κ-opioid receptor membrane protein and anti-His antibody is demonstrated in liquid by an optical microelectromechanical system utilizing electromagnetically actuated microresonators. Shift in resonance frequency due to accretion of mass on the sensitive surface of microresonators is monitored via an integrated optical re...

We evaluate the ability of hexahistidine (His6) tags on peptide and protein substrates to recruit deoxyribozymes for modifying those substrates. For two different deoxyribozymes, one that creates tyrosine-RNA nucleopeptides and another that phosphorylates tyrosine side chains, we find substantial improvements in yield, kobs, and Km for peptide substrates due to recruiting by His6/Cu(2+). Howeve...

ethan kohlberg, the jewish orientalist and specialist on shi‘a, sees the distortion in holy scriptures, including quran, inevitable. from his point of view, some quranic verses confirm this point. his second proof is the history of the quran and the time when its whole text was written down. in his viewpoint,   hadiths which prove that the quran had been written down in abu bakr’s time ore orie...

regarding the utilization of cultural and religious beliefs in the treatment of physical and mental disorders, this article presents the cases of 3 iranian psychiatric patients with severe physical and mental symptoms, preceded by a long history of different psychiatric treatments. these cases illustrate that bu relying on patients religious beliefs and faith, the therapist can increase his / h...

We present a molecular theory to study the adsorption of different species within pH-sensitive hydrogel nanofilms. The theoretical framework allows for a molecular-level description of all the components of the system, and it explicitly accounts for the acid-base equilibrium. We concentrate on the adsorption of hexahistidine, one of the most widely used tags in bio-related systems, particularly...

in its course of evolution, the sassanian rule accepted a change in temporal exigencies, condition and manner of governance of each ruler where more attention was paid to the institutional establishment, grades/ranking, titles, symbols and administrative hierarchy. in a way, the organizational manner, to a larger extent, could engulf the period into a curtain of ambiguity. one of those ranks wa...