BACKGROUND Misoprostol is an agent that may ripen the cervix in nonpregnant women. Here, we investigate whether vaginal misoprostol administered prior to intrauterine device (IUD) insertion reduces the number of failed insertions, insertion-related complications and pain during insertion. METHODS We conducted a double-blinded, multicenter randomized controlled trial among patients requesting ...

The concept of using a frameless intrauterine device (IUD) instead of the conventional plastic framed IUD is not new. Frameless copper IUDs have been available since the late 1990s. They rely on an anchoring system to retain in the uterine cavity. The clinical experience with these IUDs suggests that frameless IUDs fit better as they are thin and, therefore, do not disturb or irritate the uteru...

The intrauterine device (IUD) is an effective means of contraception,1,2 and insertion is a procedure that is commonly performed in a family physician’s office. Standard practice requires that a current pregnancy be excluded before insertion; on-site urine testing is the most obvious way to do this. This case describes an instance of inadvertent insertion of an IUD in a woman who was already pr...

Intrauterine contraception is a widely used, highly effective method of birth control. Uterine perforation is a serious albeit rare complication with the use of an intrauterine device (IUD). Although uterine perforation by the levonorgestrel-releasing intrauterine system (LNG-IUS) has already been described, no plasma LNG concentrations in this setting were reported. Neither has the management ...

The intrauterine device (IUD) is a contraceptive method which are tiny, T-shaped plastic, that placed within the uterus and left there, used all throughout world with more than 99% effectiveness rate. Pregnancy levonorgestrel-releasing system (LNG-IUS) in situ very rare. Intracavitary pregnancy an IUD can lead to higher risk of infection preterm birth. We described case live birth inserted into...

To the Editor: The review of Xu Xiong, Pierre Buekens and Elisabeth Wollast’ on IUD use and the risk of ectopic pregnancy is an interesting attempt to analyze disparate material covering a wide time span and global data. The two conclusions that 1) with an odds ratio of 1.06 “Current IUD use did not enhance the risk of ectopic pregnancy” among non-pregnant women and 2) with an odds ratio of 1.4...

Long-acting reversible contraceptive methods (LARC) are considered important to reduce the number of unintended pregnancies. Winner et al. found that women using oral contraceptives, a transdermal patch or a vaginal ring had a risk of contraceptive failure that was 20 times as high as the risk among those using LARC [intrauterine devices (IUDs), implants]. In the CHOICE cohort study of acceptan...

OBJECTIVE The purpose of this paper is to review the experience with the frameless, anchored, GyneFix copper-releasing intrauterine contraceptive devices (IUCDs/IUDs) (Contrel Europe, Belgium), and to demonstrate their high acceptability and low rate of discontinuation of use, which could contribute to current efforts that aim to reduce radically the high number of unintended pregnancies and in...

STUDY QUESTION Is there any difference in the clinical performance of the 3-year one-rod etonogestrel (ENG)- and the 5-year two-rod levonorgestrel (LNG)-releasing contraceptive implants during 3 years of insertion, and between implant and intrauterine device (IUD) contraception, in particular complaints possibly related to hormonal contraceptives? SUMMARY ANSWER The cumulative contraceptive e...

We read the article by Minig et al. [1] with great interest. The authors evaluated the efficacy of levonorgestrel-releasing intrauterine device (LNG-IUD) and gonadotropin-releasing hormone (GnRH) for treating patients with atypical endometrial hyperplasia (AEH) or early-stage endometrial cancer, grade I, who wanted to maintain their fertility. The research demonstrated that the combined therapy...