OBJECTIVE To determine the distributions of basal laminar and basal linear deposits in Bruch membrane (BM) with respect to age and early age-related maculopathy (ARM). METHODS The foveas of 41 human eyes (<60 years [n = 9]; > or =60 years [n = 32]), preserved no later than 3.5 hours post mortem, were examined using light and electron microscopy. Ten eyes met histopathologic criteria of the Al...

The Muteh gold deposit (NE of Golpaygan) in the central part of intrusive-metamorphic belt of Sanandaj-Sirjan zone comprises NW-SE trending gold-quartz vein occurred in metamorphic complex. Gold mineralization is associated with quartz veins that formed during regional deformation across the mylonitic zones in metamorphic rocks of predominantly meta-volcanic, gneiss and schist. The sulfidation ...

Dermatitis herpetiformis (DH) is an extraintestinal manifestation of coeliac disease. Untreated coeliac disease patients are known to have transglutaminase 2 (TG2)-targeted IgA deposits in the small bowel mucosa. To evaluate whether similar intestinal IgA deposits are also present in DH and whether the deposits disappear with gluten-free diet, 47 untreated and 27 treated DH patients were studie...

This paper describes occurrences of low grade, disseminated gold in sedimentary rocks and alkalic intrusions in the vicinity of the Howell Creek Structure (HCS; Price,1964) of southeastern British Columbia. The study is part of the B.C. Geological Survey’s ongoing Sediment-hosted Gold Project, which is examining occurrences throughout the province which may have similarities to gold deposits in...

We investigated the presence and localization of glycosaminoglycans in basal laminar deposit and drusen in age-related maculopathy. Conventional histological staining techniques and monoclonal antibodies specific for several glycosaminoglycans were used on paraffin-embedded human maculae. Furthermore, macular homogenates were analyzed with two-dimensional electrophoresis. Quantitative analysis ...

PURPOSE To characterize the morphology, prevalence, and topography of subretinal drusenoid deposits, a candidate histological correlate of reticular pseudodrusen, with reference to basal linear deposit (BlinD), a specific lesion of age-related macular degeneration, and to propose a biogenesis model for both lesion. METHODS Donor eyes with median death-to-preservation of 2:40 hours were postfi...