BACKGROUND Little is known about the effect of pharmacotherapy in the prevention of post-traumatic stress disorder (PTSD) relapse. AIMS To assess the efficacy and tolerability of fluoxetine in preventing PTSD relapse. METHOD This was a double-blind, randomised, placebo-controlled study. Following 12 weeks of acute treatment, patients who responded were rerandomised and continued in a 24-wee...

OBJECTIVE Review and examine existing research, current strategies, and directions for future research on smoking cessation relapse and relapse prevention in pregnancy and postpartum. METHODS A MEDLINE/PubMed search in 2002 and 2003 for articles containing the key words "smoking," "pregnancy," "cessation," and "cessation relapse prevention" and references of retrieved papers yielded a review ...

Cariprazine, a dopamine D3/D2 receptor partial agonist with preference for D3 receptors, has demonstrated efficacy in randomized controlled trials in schizophrenia. This multinational, randomized, double-blind, placebo-controlled, parallel-group study evaluated the efficacy, safety, and tolerability of cariprazine for relapse prevention in adults with schizophrenia; total study duration was up ...

Sexual offender treatment has evolved considerably over the course of the last two decades. The introduction of the Relapse Prevention (RP) model to the field considerably advanced the provision of effective service (Hanson, Gordon, Harris, Marques, Murphy, Quinsey, & Seto, 2002). However, over the course of the 1990s some (e.g., Hudson & Ward, 2000) began to criticize the RP model due to a num...

THE TREATMENT OF VIOLENT BEHAVIOUR PROBLEMS OVER THE LAST TWO decades has increasingly utilised a cognitive-behavioural approach. Relapse Prevention (RP) (Marlatt & Gordon 1985) is a variety of cognitive-behavioural intervention which is gaining increasing currency in the area of violent behaviour, including sexual offending (Pithers 1990) and domestic violence (Jennings 1990). Given the situat...

A multicomponent smoking relapse prevention treatment based on Marlatt and Gordon's (1980) model of the relapse process was developed and evaluated. Behavior-analytic methods were used to develop assessment instruments, training situations, and coping responses. The prevention components were presented in the context of a basic broad-spectrum stop-smoking program, and were compared with the bas...