Axillary lymph node (ALN) metastasis is a key step of tumor progression in breast cancer and is associated with an unfavorable prognosis. However, the mechanisms of this process are not well understood. Proteomic technologies have led to identification of specific protein markers and a better understanding of the cellular processes. To explore this, differential protein expression was analyzed ...

BACKGROUND Taenia multiceps is a cestode parasite with its larval stage (metacestode), Coenurus cerebralis, mainly encysts in the central nervous system of sheep and other livestock causing cerebralis coenurosis. Since, treatment of coenurosis with chemotherapy showed little effect and surgical removal of cysts is not advisable in field conditions, vaccination is useful to control coenurosis. P...

Mitotane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chloro-phenyl) ethane (o,p'-DDD), is a compound that represents the effective agent in the treatment of the adrenocortical carcinoma (ACC), able to block cortisol synthesis. In this type of cancer, the biological mechanism induced by this treatment remains still unknown. In this study, we have already shown a greater impairment in the first steps o...

background: viscerotropic leishmaniasis caused by leishmania tropica poses a significant prob­lem in the diagnosis and treatment management. since differential gene expression is more im­portant in outcome of the infection, we employed proteomic approach to identify potential pro­teins involved in visceralization of l. tropica . methods: the proteomes profiling of l. tropica isolated from cutan...

Feeding farmed Artemia with yeast heat shock proteins is a novel way to protect them from stress conditions during the culture.  In this study, the effect of feeding with stressed new identified Saccharomyces cerevisiae strain YG3-1 yeasts (containing induced heat shock proteins) on the survival of Artemia in stress conditions, was evaluated. For this purpose, heat shock proteins 82 (Hsps 82) o...

abstract background: asterocytoma is the most common primary human brain tumor which has the most lethal hazard among tumors in human central nervous system. heat shock proteins play an active role in cancer cells pathways through their effects on tumor cell proliferation, tumor differentiation, malignancy, metastasis, and cell death. hsp 70 is a 70 kd protein that its expression change has bee...

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