Background: Red blood cells (RBCs) undergo biochemical and morphologic alterations during storage that are known as the storage lesions causing decreased RBC quality and are correlated with transfusion reactions in certain groups especially in infants and critically ill patients. Microvesicles (MVs) as one of storage lesions may be derived from various cell types and have key roles in several...

Human red blood cells sensitized with concanavalin A became bound to homologous peripheral blood monocytes. Binding occured at a concentration of 10(5) molecules of tetrameric Con A per red blood cell (RBC) and increased with additional Con A. RBC binding began within 5 min and was maximal at 90 min. Phagocytosis of sensitized RBCs was minimal. RBC attachment was prevented by 0.01 M alpha-methy...

We have used a sensitive new technique to assess the mechanism(s) of adrenergic inhibition of rainbow trout (Oncorhynchus mykiss) red blood cell (RBC) carbon dioxide excretion in vitro. The effect was only apparent using blood acidified to simulate metabolic acidosis. Red blood cell CO2 excretion was inhibited in a dose-dependent manner by physiologically relevant concentrations of noradrenalin...

background: several factors influence on the outcome  of ischemic stroke. the aim of this study was determination the relationship  between stroke mortality and red blood cell parameters. methods: this cross-sectional  study was conducted  from 2011 july to june 2012. for all patients with ischemic stroke in middle  cerebral  artery  (mca)  territory, the  cell blood count test was performed. w...

The RBC histogram is an integral part of automated hematology analysis and is now routinely available on all automated cell counters. This histogram and other associated complete blood count (CBC) parameters have been found abnormal in various hematological conditions and may provide major clues in the diagnosis and management of significant red cell disorders. In addition, it is frequently use...

In order to simulate red blood cell (RBC) behaviors in a flowing blood, we developed a mathematical model of an elastic RBC and their multi-body interaction based on the minimum energy principle. The results showed realistic behavior of multiple RBCs in a straight artery as well as single RBC behavior in a uniform shear flow including tumbling and tank treading motion observed in experiments. N...

Introduction Red cell transfusion is an extremely common medical intervention. In the United States, more than 16 million red blood cell (RBC) units are transfused annually to 3.4 million patients.Worldwide, 85 million units of blood are collected per year. In Northern England, about 50% of units are given tomedical patients, and 40% to surgical patients; hip replacement and coronary artery byp...

background: studies have demonstrated that sickle cell trait can be found in an asymptomatic healthy carrier with normal complete blood count (cbc) and red blood cell (rbc) indices. according to iranian ministry of health bulletin instructions, prenuptial thalassemia screening program (tsp) primarily depends on rbc indices which are measured through a routine cbc. only when these levels are bel...

Hidden blood loss typically occurs following total hip arthroplasty (THA) and total knee arthroplasty (TKA) and is thought to be related to free fatty acid (FFA). To study the effect of linoleic acid on red blood cells and to examine the pathogenesis of hidden blood loss in vivo, we generated an animal model by injecting linoleic acid into the tail veins of rats. We collected blood samples and ...