background chromosomal abnormality plays an important role in different types of miscarriages. objectives the present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent abortion (ra), spontaneous abortion (sa) and still birth (sb). patients and methods in this retrospective study, the frequency of chromosomal aberrations was investigated among 26...

background: congenital toxoplasmosis is an important cause of spontaneous abortion worldwide. however, there is limited information on detection and genotypic characterization of t. gondii in women with recurrent spontaneous abortion (rsa). the aim of this study is molecular detection and genotypic characterization of t. gondii in formalin-fixed, paraffin-embedded fetoplacental tissues (ffpts) ...

The etiology of recurrent spontaneous abortion (RSA) is still unexplained. Many couples do not find the cause of their RSA at all. The purpose of this research was to evaluate the association between recurrent pregnancy loss and previous (cured prior to pregnancy) acute/chronic genitourinary infections in both parents. Couples (226) having two or more (up to six) spontaneous abortions were anal...

introduction: recurrent abortion (ra) may be a consequence of aberrant expression of immunological factors during pregnancy. although the relative importance of immunological factors in human reproduction remains controversial, substantial evidence suggests that autoantibodies contribute to reproductive failure. production of such antibodies is under the control of cytokines; and leptin, beside...

Chromosomal abnormalities are one of the major causes of infertility in man and woman. A couple with history of recurrent spontaneous abortion (RSA) was referred to our laboratory for chromosomal analysis. The analysis revealed normal 46,XY karyot ype in male and a novel balanced translocation 46,XXt(4;20)(q11;p13) in female partner. This translocation with breakpoints has not been reported in ...

it has been recognized that acute and chronic stress has an impact on the immune system. acute stress may have a stimulating effect on the immune system, while in the case of chronic stress specially depression, the immune system could be down-regulated. however, an association between depression and a higher number of circulating white blood cells with increased activity has been reported. ele...

background: recurrent spontaneous abortion impacts almost 1% of couples. the sera from women with unexplained recurrent spontaneous abortion (ursa) have toxic effects on embryos that grow in the uterus. therefore, the abnormal condition of the uterus may also affect sperm qualities. objective: the objectives of this study were to search if these sera could induce dna denaturation in sperm nucle...

the measurment of various cytokines may provide a different tool for evaluation of the immune system. recent investigations have shown that the number and function of peripheral natural killer cells (nk- cells) increase during early pregnancy in women with a history of unexplained recurrent spontaneous abortions (rsa). nk-cells activity may be responsible for some cases of rsa. the objective of...

Recurrent Spontaneous Abortion (RSA), Habitual Abortion or Habitual Miscarriage is the loss of 3 or more consecutive pregnancies before the 24 week of gestation. RSA occurs chiefly due to either a problem with the pregnancy or when there is a problem in the environment where it implants and further development occurs. 10-15 % of women with recurrent early pregnancy loss have congenital uterine ...