Epilepsy affects 1-2 % of the population. For 30 % of these patients, their syndrome will be refractory to medical treatment. To improve our understanding and treatment of the epilepsies, we need to develop clinically relevant animal models. As temporal lobe epilepsy is often preceded by prolonged febrile seizures and in our population associated with a focal cortical dysplasia, we hypothesised...

febrile seizure is the most common form of childhood seizures that occur in 2-5% of them. the purpose of this study was to compare serum sodium level in first simple, multiple and recurrent febrile con-vulsions to answer whether serum sodium levels can predict febrile seizure recurrence in 24 hours and in other febrile episodes? in a retrospective study, sodium serum levels of all children aged...

OVERVIEW Simple febrile seizures that occur in children ages 6 months to 5 years are common events with few adverse outcomes. Those who advocate therapy for this disorder have been concerned that such seizures lead to additional febrile seizures, to epilepsy, and perhaps even to brain injury. Moreover, they note the potential for such seizures to cause parental anxiety. We examined the literatu...

Background: Febrile seizure (FS) is one of the most common neurologic disorders in children. Electrolyte imbalance especially hyponatremia may have an important role in triggering the febrile seizure. The measure of serum electrolytes will be useful in predicting the further seizure. The aim of this study was to investigate the effect of relative hyponatremia (RH) on the risk of recurrent febri...

how to cite this article: delpisheh a, veisani y, sayehmiri k, fayyazi a. febrile seizures: etiology, prevalence, and geographical variation. iran j child neurol. 2014 summer; 8(3):30-37.   abstract objective febrile seizures (fss) are the most common neurological disorder observed in the pediatric age group. the present study provides information about epidemiological and clinical characterist...

A child with a febrile seizure is a common cause of admission in a general paediatric ward in Malaysia. We set out to look prospectively into the clinical and epidemiological features of these children. A total of 117 children were admitted into the study. The ratio of boys to girls were 1.5:1.0. The racial breakdown was 62.4% Malays, 26.5% Indians, 8.5% Chinese and 2.6% others. The first febri...

OBJECTIVE To assess the efficacy of various medications in the prevention of recurrent febrile seizures. STUDY DESIGN A meta-analysis of all published randomized, placebo-controlled trials of the preventive treatment of febrile seizures published in English; 45 articles were found, but only 9 trials were randomized and placebo-controlled--4 using phenobarbital; 3, diazepam; 1, pyridoxine; and...

Background: Febrile seizure (FS) is one of the most common neurologic disorders in children. Electrolyte imbalance especially hyponatremia may have an important role triggering febrile seizure. The measure serum electrolytes will be useful predicting further seizures. This study aimed to investigate effect relative on risk recurrent Methods: prospective was performed 115 children (6-60 months) ...

it is known that neuropeptide y which is widely distributed throughout the central nervous system is able to prevent seizures in animals. there are limited studies about the role of neuropeptide y in febrile seizures. this study was conducted to evaluate the association between plasma neuropeptide y level and febrile seizures in children. seventy six patients with typical and atypical febrile s...