This brief review will summarise our present knowledge on the possible role of human minor histocompatibility antigens (mHags) in graft failure. Following a short introduction on the possible nature of human mHags some in vitro studies dealing with graft failure and rejection will be discussed. To understand the possible impact of mHag disparity between organ donor and recipient on the outcome ...

The successes of thoracic transplantation have led to the expansion of indications and a subsequent growth in demand for a short supply of organs. In response to this disparity, the criteria for organ donation have been liberalized. Despite these difficult challenges, with advances in surgical techniques and perioperative care of both the donor and recipient, outcomes have continued to improve ...

background hepatitis c virus (hcv) infection still exists as a health concern among the transplant patients. because of the severity of the disease, different responses to treatment, and side effects resulting from long therapeutic period, determination of genotypes and viral loads can help choose the best treatment protocols. objectives this study aimed to determine the hcv genotypes and its d...

INTRODUCTION Allograft failure due to immunological or non-immunological causes or a combination and patient death after transplantation are the 2 major causes of renal transplant loss. This paper reviews the various causes of allograft failure and explores strategies for its prevention. RESULTS Immune mechanisms of renal allograft failure are those mediated by acute and chronic rejection and...

background hepatitis c virus (hcv) infection is the most significant source of chronic liver diseases in the globe. about 170 million individuals are infected by hcv worldwide. the reported prevalence of hcv in different areas of khyber pakhtunkhwa (kp) ranges from 4.1 to 36%. objectives the current study aimed to analyze the true prevalence of hcv infection in khyber pakhtunkhwa, pakistan. mat...

Abstract Mycosis Fungoides (MF), the most common type of cutaneous T-cell lymphoma, typically presents with an erythematous or dyspigmented rash that can progress to tumors and ulcerations on skin. MF is more in skin color (SOC) patients, where it earlier at a higher T-stage. This has led poorer prognosis SOC poorest African Americans. The pathogenesis regarding this racial disparity remains po...

results urban patients were more likely to receive supplementary information and being strongly encouraged by their nephrologists to seek transplant. all participants acknowledged “independence” as the main advantage of transplantation. increased freedom to travel and improved life expectancy were mentioned only among the urban groups. the main themes in all groups regarding perceived barriers ...

background: lung diseases are one of the major causes of morbidity and mortality after renal transplantation. the aim of the study is to define the risk factors for infectious and noninfectious pulmonary complications in kidney transplant patients. materials and methods:we prospectively studied 267 patients after renal transplantation. the kidney recipients were followed-up for the development ...

background : one of the major health policy issues, in the both developed and developing countries, is the equality in the distribution of health resources. the aim of this study was to investigate the disparity in the distribution of health physical resources across the provinces of iran in 2001 and 2011. methods : this was a cross-sectional retrospective study which investigated inequality in...