3-methylcholanthrene (MC)-induced mouse 10 embryonal (ERSs) and 24 pleomorphic rhabdomyosarcomas (PRSs) of the dermis were examined immunohistochemically for nuclear reactivity of Mdm2, p53, and proliferating cell nuclear antigen (PCNA). ERSs were microscopically present in the rhabdium layer of the dermis from 10 to 13 weeks post injection (PI), and PRSs developed from 13 weeks PI. Moderate to...

CABRI is an experimental pulse reactor, funded by the french Institute for Radiological protection and Nuclear Safety (IRSN) operated CEA at Cadarache nuclear center, France. Its aim to study thus better understand RIA (Reactivity-Initiated Accident) effects on fuels. The restart of reactor in 2015 offers opportunity validate tools involving multiphysic calculation schemes reactivity insertions...

Abstract—Analysis of the uncertainty quantification related to nuclear safety margins applied to the nuclear reactor is an important concept to prevent future radioactive accidents. The nuclear fuel performance code may involve the tolerance level determined by traditional deterministic models producing acceptable results at burn cycles under 62 GWd/MTU. The behavior of nuclear fuel can simulat...

  Background and Objective: Histological grading has prognostic and therapeutic implications in meningioma. However, histological criteria are sometimes not fulfilled to predict the biological behavior of meningiomas. P63 gene is a novel P53 family member, known as tumor suppressor factor, with multiple isoforms and shows high expression in many normal and neoplastic human tissues. In this stu...

In this study, the effective reactivity and burnup analyses have been performed for heterogeneous three-dimensional high-temperature gas-cooled thorium reactor (HTGR) which has 60 MWth full core geometry by using continuous-energy multi-purpose Monte Carlo particle transport Serpent code with ENDF/ B-VII data libraries. Nuclear fuel selected as 50 % ThO2+50% RG-PuO2. Firstly, three different qu...

background and objective: histological grading has prognostic and therapeutic implications in meningioma. however, histological criteria are sometimes not fulfilled to predict the biological behavior of meningiomas. p63 gene is a novel p53 family member, known as tumor suppressor factor, with multiple isoforms and shows high expression in many normal and neoplastic human tissues. in this study,...

Nuclear stiffness, expressed as a hardness derivative, appears to be a good measure of the slope of global hardness. The authors analyze molecular states for which hardness has a maximum value. Maximum hardness principle (MHP) has been discussed. At the ground state hardness function does not obtain a maximum value versus spatial coordinates within a constant number of electrons (N), but is so ...