Background: IgE is closely related to the development of allergies. However, the poor relationship between the specific IgE level and the severity of allergic diseases suggests the possibility of functionally different IgE isoforms. With this in mind, rat basophilic leukemia (RBL)-2H3 activation was analyzed with each type of rat IgE for two parameters, exocytosis and IL-4 mRNA production. RBL-...

Penelitian ini bertujuan untuk meningkatkan hasil belajar IPS, yang dilaksanakan di SDN 56 pekanbaru pada semester genap TA 2022/2023 dengan subjek siswa kelas kontrol IV A 11 orang dan eksperimen B siswa. Bentuk penelitian eksperimen-group prettest-posttest menerapkan model pembelajaran Resource Based Learning (RBL). Masalah dari adalah rendahnya IPS SD negeri pekanbaru, hal terlihat prestes. ...

The ability of conjecturing thinking skill is very important in the industrial era 4.0. Conjecturing skills are to make strong guesses or predictions on problem solving. This also strongly related generalizing from a specific truth broad truth. Therefore this study, Research-Based Learning model which integrated with STEM approach (Science, Technology, Engineering, Mathematics) will be applied ...

Tumor necrosis factor alpha (TNF-α), a central mediator of the inflammatory response, is released from basophilic cells and other cells in response to a variety of proinflammatory stimuli. Vialinin A is a potent inhibitor of TNF-α production and is released from RBL-2H3 cells. Ubiquitin-specific peptidase 5 (USP5), a deubiquitinating enzyme, was identified as a target molecule of vialinin A and...

We describe the cloning of a cDNA from the rat basophilic leukaemia cell line (RBL.2H3) encoding a novel member of the Rab family of small GTP binding proteins. The novel clone, which we call Rab8b, is most highly related to the Rab8 family with substantial divergence in the variable C-terminal domain. Northern blot analysis reveals highest levels of expression of Rab8b in the spleen, testis an...

This study investigated the effects of guarana seed extract (GSE) on an anti-allergic mechanism. GSE orally administered inhibited the anti-dinitrophenol IgE-induced passive cutaneous anaphylaxis reaction in mice. Furthermore, it inhibited the degranulation of rat basophilic leukemia RBL-2H3 cells. It had no cytotoxicity on RBL-2H3 cells. These results show that GSE is a candidate for effective...

Early endosomes and a perinuclear, Rab-11-positive compartment have been implicated in the recycling of internalized receptors. In this study, we show that synaptotagmin III (Syt III), a member of the Syt family of proteins, is required for the formation and delivery of cargo to the perinuclear endocytic recycling compartment (ERC). We demonstrate that rat basophilic leukemia (RBL-2H3) mast cel...

A 16kb lTlC FeRAM testchip is designed and fabricated in a 0.35pm FeRAM process. The testchip uses a reference generation scheme that balances fatigue evenly between memory cells and reference cells, hence providing the lTlC cell with 2T2C robustness to fatigue. The testchip achieves an access time of 6211s at 3V. Introduction Reference generation is an essential component of lT lC Ferroelectri...

In this study, a new approach to laser-induced breakdown spectroscopy (LIBS) data modeling using multiway algorithms was investigated. Two case studies, parallel factor analysis (PARAFAC) and unfolded-partial least-squares with residual bilinearization (U-PLS/RBL) were used in (1) the determination of Al, Cu, Fe samples reference material printed circuit board (PCB) from electronic waste (2) Ca...

We prove that the sequent calculus LRBL for residuated basic logic RBL has strong finite model property, and that intuitionistic logic can be embedded into basic propositional logic BPL. Thus RBL is decidable. Moreover, it follows that the class of residuated basic algebras has the finite embeddability property, and that BPL is PSPACE-complete, and that intuitionistic logic can be embedded into...