This study was designed to investigate the association of the IL-8-251 T > A gene polymorphism with clinicopathological features and the prognostic role of the gene polymorphism in patients with gastric adenocarcinoma. The gene polymorphism was detected by the polymerase chain reaction-restriction fragment length polymorphism method, followed by univariate and multivariate analyses to elicit it...

1 Department of Clinical Epidemiology and Medical Technology Assessment, University Hospital Maastricht, Maastricht, The Netherlands 2 Department of Epidemiology, Maastricht University, Maastricht, The Netherlands 3 Department of Health Organization Policy and Economics, Maastricht University, Maastricht, The Netherlands 4 Care and Public Health Research Institute, Department of General Practic...

W artykule przedstawiono wyniki badań procesu odwadniania masy wydobywczej zawierającej bursztyn, za pomocą wibroklasyfikatora. Opisano cechy schematu technologicznego wydobywania bursztynu w odniesieniu do punktów zaopatrzenia wodę. Badano stan równowagi cieczy komorze wibroklasyfikatora różnych warunkach zwilżalności sita: ciecz niezwilżająca włókien sita; płyn zwilżający włókna cienka warstw...

W historii dzieła misyjnego Kościoła, realizowanego nieprzerwanie od dwóch tysięcy lat, wiele razy pojawiały się kolejne paradygmaty misyjności, a w konsekwencji nowe metody misyjne oraz innowacyjne środki odziaływania misyjnego. Znajomość zakresu i znaczenia owych paradygmatów metod pozwala dostrzec dynamiczność realizacji Kościoła nie tylko wymiarze geograficznym, ale nade wszystko zrozumieć ...

Metastatic melanoma is an aggressive cancer with very low response rate against conventional chemotherapeutic agents such as dacarbazine (DTIC). Inhibitor of Rb–Raf-1 interaction RRD-251 was tested against the melanoma cell lines SK-MEL-28, SK-MEL-5, and SK-MEL-2. RRD-251 was found to be a potent inhibitor of melanoma cell proliferation, irrespective of V600E B-Raf mutation status of the cell l...

Moral text processing was used as an ecologically valid method for assessing implicit and explicit moral understanding and development. The authors tested undergraduates, seminarians, and graduate students in political science and philosophy for recall of moral narratives and moral expository texts. Multivariate analyses of covariance using educational experience as an independent variable, age...

All-trans-retinoic acid (RA) is known to induce terminal granulocytic differentiation and cell cycle arrest of HL-60 cells. Responding to an RA-induced cytosolic signaling machine, c-Raf translocates to the nucleus, providing propulsion for RA-induced differentiation. This novel mechanism is not understood, but presumably reflects c-Raf binding with nuclear gene regulatory proteins. RRD-251 is ...

Introduction:  IL-8 is one of the pro-inflammatory cytokines which can play an essential role in the pathogenesis of chronic rhinosinusitis (CRS) as well as nasal polyposis (NP). The ability of individuals in producing IL-8 is partially determined by IL-8-251 A/T polymorphism. Hence, the aim of the present study was to investigate the association between IL-8-251 A/T and CXCR2 +1208 C/T genes ...

CONTENTS INTRODUCTION 237 TRANSFERS INVOLVING EUKARYOTES 239 Phylogenetic Congruency Test 239 Pitfalls Involving Paralogies 241 Pitfalls Involving Unequal Razes 242 Convergent Replacements 243 Tests of Significance 244 MOBILE GENETIC ELEMENTS 244 CHROMOSOMAL GENES IN BACTERIA 245 Mosaic Nature of the E. coli chromosome 245 Salmonella and the Criteria of GC Content 247 Codon Bias 249 Other Bacte...