INTRODUCTION Langerhans' cell histiocytosis is a proliferative histiocytic disorder of unknown cause originating from dendritic cells. CASE PRESENTATION The authors report a case of Langerhans' cell histiocytosis in a 48-year-old man with multisystemic disease presentation, including liver involvement. CONCLUSION Hepatic involvement is an uncommon feature in this rare disease and there is n...

background this study aimed to explore demographic characteristics and clinical presentations of celiac disease (cd) in northeastern iran. methods this was a cross-sectional retrospective study of 193 adults with cd who presented to mashhad university gastroenterology clinic between 2008 and 2013. patient data that included mode of presentation and the presence of any concomitant illnesses were...

Cutaneous leishmaniasis(CL) is referred to a group of diseases because of the varied clinical presentation, ranging from small cutaneous nodule to wide spread mucosal destruction. The nose is rarely involved by CL in even in endemic region. In this report we describe a rare rhinophymatous presentation of CL from a non-endemic region which was diagnosed by fine needle sampling and treated with M...

thyroglossal duct cyst is a well-known congenital entity, and its embryonic development and clinical presentation are well understood. very little can be added to the classic material found in the world literature. rare cases of unusual clinical presentation have also been reported. our case of endolaryngeal thyroglossal duct cyst is reported because of its unique endolaryngeal presentation, ha...

background/objective: the aim of the present preliminary study was to assess the demographic, clinical, paraclinical, microbiological, echocardiographic, and therapeutic profile as well as in-hospital outcome of patients with infective endocarditis at a referral center for various infectious diseases in iran.methods: required demographic, clinical, plausible complications and paraclinical data ...

multiple sclerosis (ms) is a demyelinating disease of the central nervous system, with unknown etiology in which both genetic and environmental factors are thought to be involved. the human leukocyte antigen (hla) system provides a set of genetic markers which lend themselves to systematic study. in iran, hla-a24, hla-dr2, and hla- dr15 are significantly increased in ms patients. the disease al...