Activity-regulatedcytoskeleton-associated protein (Arc) protein is implicated as a master regulator of long-term forms of synaptic plasticity and memory formation, but the mechanisms controlling Arc protein function are little known. Post-translation modification by small ubiquitin-like modifier (SUMO) proteins has emerged as a major mechanism for regulating protein-protein interactions and fun...

The immediate-early gene Arc is rapidly expressed in response to neuronal activity and is thought to be involved in mechanisms of synaptic plasticity. The function of Arc in these processes remains unknown. The present study demonstrates that during an in vitro neural correlate of eyeblink classical conditioning, there is a rapid and transient increase in levels of Arc protein that require acti...

Purpose: Volumetric intensity-modulated arc therapy (RA) allows for rapid delivery of highly conformal dose distributions. In this study, planning and dosimetry of RAwere compared with conventional intensity-modulated radiation therapy (IMRT) plans of head-and-neck cancer patients. Materials and Methods: Computed tomography scans of 12 patients who had completed IMRT for advanced tumors of the ...

[1] The Tonga-Kermadec subduction system in the southwest Pacific preserves a series of crustal elements and sediments which have recorded subduction initiation, rift, and back-arc basin formation. The Norfolk Basin is the farthest landward of all back-arc basins formed in the Tonga-Kermadec region and may preserve the earliest record of subduction initiation regionally. For the Norfolk Basin, ...

High voltage arc discharge is a method to pasteurize liquid foods by applying rapid discharge voltages through an electrode gap below the surface of aqueous suspensions of microorganisms. Inactivation of microorganisms and enzymes contained in food products by electrical discharges began in the 1920s with the electropure process for milk. This process consisted of passing an electrical current ...

Purpose: The aim of this study was to dosimetrically evaluate and compare double arc RapidArc (RA) with conventional IMRT (7 fields) plans for irradiation of locally advanced head and neck cancers (LAHNC), focusing on target coverage and doses received by organs at risk (OAR). Methods: Computed tomography scans of 20 patients with LAHNC were obtained. Contouring of the target volumes and OAR wa...

Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory. Despite evidence that Egr family members can control Arc transcriptional regulation, demonstration of a selective role of Egr1 alone is lacking. We investigated the extent to which activity-dependent Arc expression is dependent on Egr1 by anal...

Parallel computing on interconnected workstations is becoming a viable and attractive proposition due to the rapid growth in speeds of interconnection networks and processors. In the case of workstation clusters, there is always a considerable amount of unused computing capacity available in the network. However, heterogeneity in architectures and operating systems, load variations on machines,...

The chapter covers general issues related to power quality in Electric Arc Furnaces. The use of electric arc furnaces (EAF) for steelmaking has grown dramatically in the last decade. Of the steel made today 36% is produced by the electric arc furnace route and this share will increase to 50 by 2030. The electric arc furnaces are used for melting and refining metals, mainly iron in the steel pro...