This is a multi-center qualitative study embedded within larger multiphase feasibility investigating the management benign paroxysmal positional vertigo (BPPV) in acute traumatic brain injury(TBI). Evidence has shown methods have place studies as they can improve validity of future trial. Our primary objective was to explore acceptability trial processes such recruitment, randomization and inte...

background: despite major advances in assisted reproductive techniques, the implantation rates remain relatively low. some studies have demonstrated that intrauterine infusion of granulocyte colony stimulating factor (g-csf) improves implantation in infertile women. objective: to assess the g-csf effects on ivf outcomes in women with normal endometrial thickness. materials and methods : in this...

background: many workers suffer from low-back pain. type and severity of spinal complaints have relationship with work load. lack of adherence to ergonomics recommendations among the important causes of low-back pain. objective: to assess the effect of 3 ergonomics training programs on the prevalence of lowback pain among workers of an iranian automobile factory. methods: in a parallel-design 4...

The double blind randomized controlled trial (RCT) is considered the gold-standard in clinical research. Evidence for the effectiveness of therapeutic interventions should rely on well conducted RCTs. The importance of RCTs for clinical practice can be illustrated by its impact on the shift of practice in hormone replacement therapy (HRT). For decades HRT was considered the standard care for al...

• Four anti-epileptic drugs (AEDs) have been approved for the adjunctive treatment of primary generalized tonic-clonic seizures (PGTCS) in adults: topiramate [TPM], lamotrigine [LTG]/ lamotrigine-XR [LTG-XR], levetiracetam [LEV], and perampanel [PER]. • Five randomized-controlled trials were conducted to support these approvals [1-5]. Lamotrigine-XR applies to the US but not the EU. • These tri...

RESEARCH DESIGN AND METHODS — After completion of a 6-month randomized controlled trial (RCT) evaluating CGM in children, adolescents, and adults with type 1 diabetes, CGM was initiated in the trial’s control group with less intensive training and follow-up than was included in the RCT. Subjects had an outpatient training session, two follow-up phone calls, and outpatient visits at 1, 4, 13, an...

In a recent issue of CHEST (June 2015), we read with interest the randomized controlled trial (RCT) by Kirakli et al comparing adaptive support ventilation (ASV) with pressure assist/control ventilation (P-ACV) for the entire duration of mechanical ventilation (MV) in a cohort of 229 patients in the medical ICU. The study showed a shorter duration of the weaning process and total MV in the ASV ...

The importance of treating traumatic brain injury (TBI) is well known worldwide. Although many studies have been conducted in this topic, there is still much uncertainty about the effectiveness of surgical treatment in TBI. Recently, good randomized controlled trial (RCT) papers about the effectiveness of decompressive craniectomy (DC) in TBI has been published. In this article, we will review ...

background and objective: genital warts, due to specific types of the human papillomavirus, have long been regarded as one of the most important causes of cervical cancer and one of the most common cause of sexually transmited diseases (stds).  over the years, it has been the focus of several studies in order to find the best effective approach to eradicate the virus, however there are still co...