نتایج جستجو برای: randomized clinical trial rct
تعداد نتایج: 1464736 فیلتر نتایج به سال:
هدف: در این مطالعه به بررسی اثر سولفات روی خوراکی در درمان زگیل های متعدد در بیماران مراجعه کننده به کلینیک پوست بیمارستان بوعلی در سالهای 89-1388 پرداختیم. روش مطالعه: این مطالعه یک بررسی مداخله ای (interventional) از نوع کارآزمایی بالینی تصادفی (double blind randomized clinical trial) است که بر روی 30 بیمار مبتلا به زگیل های متعدد مراجعه کننده به کلینیک پوست بیمارستان بوعلی در سالهای 89-1388...
This critical review examines efficacy of CILT in comparison to traditional treatment methods for adults with aphasia as well as the efficacy of modified versions of the original CILT protocol. Study designs include: individual series pre-post treatment (3), mixed randomized clinical trial (RCT) (2), mixed non-randomized clinical trial (NRCT) (2), mixed randomized block (1) designs. Overall, re...
Randomized controlled trials (RCT) are the optimal study design to answer intervention questions. The authors evaluated the number, quality, and coverage of RCT in nephrology. MEDLINE was searched using the relevant medical subject headings for nephrology and 12 major specialties in internal medicine, limited by "randomized controlled trial" as a publication type. A random selection of 160 RCT ...
Clinical trials are one of the most valuable sources of scientific evidence for improving the practice of medicine. The Trial Bank project aims to improve structured access to trial findings by including formalized trial information into a knowledge base. Manually extracting trial information from published articles is costly, but automated information extraction techniques can assist. The curr...
Randomized clinical trial (RCT) study design leads to one of the highest levels of evidence, and is a preferred study design over cohort studies, because randomization reduces bias and maximizes the chance that even unknown confounding factors will be balanced between treatment groups. Recent randomized clinical trials and observational studies in amblyopia can be taken together to formulate an...
OBJECTIVE The researchers sought to assess whether the widely used 1994 Cochrane Highly Sensitive Search Strategy (HSSS) for randomized controlled trials (RCTs) in MEDLINE could be improved in terms of sensitivity, precision, or parsimony. METHODS A gold standard of 1,347 RCT records and a comparison group of 2,400 non-trials were randomly selected from MEDLINE. Terms occurring in at least 1%...
This study deals with the question of how to model health effects after the cessation of a randomized controlled trial (RCT). By using clinical trial data on severe congestive heart failure patients, we illustrate how survival beyond the cessation of an RCT can be predicted based on parametric survival models. In the analysis, we compare predicted survival and the resulting incremental cost-eff...
OBJECTIVES To explore long-term effects of treatment and prognostic relevance of variables assessed at baseline and during the European secondary progressive multiple sclerosis (SPMS) trial of interferon beta 1b (IFNB-1b). METHODS We assessed 362 patients (60% female; median age 41 years; Expanded Disability Status Scale (EDSS): 5.5; 51% randomized to IFNB-1b) for their EDSS and treatment his...
In this section of the series on orthodontic research we intend to give a brief outline of how to carry out a randomized controlled trial (RCT). The RCT is one of the most simple and powerful research tools in which people are allocated at random to receive one of several clinical interventions. We hope that this will not only provide information to anyone who is aiming to carry out research of...
abstract background: premenstrual syndrome (pms) can cause problems in daily work and relationships. materials and methods: eighty‑six women were randomly assigned to two intervention groups and one control group. patients were asked to fill out the pms daily symptoms record for 2 months, and then the participants were randomly assigned to one of the three study groups. medical intervention was...
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