BACKGROUND Radium-223 prolongs overall survival in patients with castration-resistant prostate cancer (CRPC) and symptomatic bone metastases, regardless of prior docetaxel. Whether or not chemotherapy can be safely administered following radium-223 treatment is of clinical importance. An exploratory analysis of prospectively collected data, from the ALSYMPCA (ALpharadin in SYMptomatic Prostate ...

Background: Ondo city in Ondo State Nigeria includes Ondo East and West could be described as a research city due to antecedent number of research institutes. Materials and Methods: Dose due to radioactivity content of soil samples from sixteen waste dump sites in Ondo, Southwestern Nigeria was determined using gamma-ray spectrometer in order to evaluate the radiation hazard health profile and ...

to assess the environmental radioactivity levels and hence to determine the population exposure in kutubdia island, bangladesh the sediment samples were analyzed by using gamma ray spectrometry. in those sediment samples the average activity concentration of natural radionuclides 238u, 232th and 40k were found 15.39±1.67, 38.35±0.76 and 475.51±21.15 bq/kg respectively. the activity concentratio...

Marie Curie gave outstanding contributions to science and society that were recognized still in her lifetime. In particular, the discovery of radium completely changed the therapeutic methods for treatment of cancer and other diseases, and allowed the development of radiotherapy and nuclear medicine. Radium was also used in many non-medical applications. Radium applications fostered the growth ...

Within this paper is presented information about current study of radon and radium analysis in self-bottled drinking water from the public fountain “Elixir” Moklište area, city Kavadarci. Obtained results for measurements, preventive method taken samples, ranged 3.40 up to 3.69 Bq·l–1, while values typical samples 2.60 3.62 Bq·l–1. Radon concentration measured obtained way showed lower than cor...

BACKGROUND Myelosuppression is common in patients with progressive castration-resistant prostate cancer and bone metastases. Radium-223 prolongs overall survival in these patients but may cause myelosuppression; understanding risk factors will improve clinical decision making. We describe hematologic safety of radium-223 in ALSYMPCA and post hoc analyses identifying patients at increased risk f...

IN THE years 1903 and 1904, shortly after the discovery of radium, small amounts of radioactivity were discovered in the water of the health springs of the spas of Germany and France. It was found that this radioactivity was due to radon, a gaseous daughter-product of radium. The supposed medicinal benefit from drinking of, or bathing in natural springwater was ascribed to the radon. A medical ...

BACKGROUND Radium-223 dichloride, or radium-223, is a first-in-class alpha emitter that selectively targets bone metastases with high-energy, short-range alpha particles and is approved for the treatment of patients with castration-resistant prostate cancer (CRPC), symptomatic bone metastases, and no known visceral metastatic disease. Nurses are essential in educating patients about radium-223....