INTRODUCTION Radiotherapy has proven to be an effective treatment when used alone or with other therapies. However, underuse of radiotherapy has been observed in various studies. The objective of this investigation was to assess the use of radiotherapy as initial treatment for lung cancer in a southern region of Europe. METHODS A systematic review of lung cancer treatment guidelines and obser...

BACKGROUND In recent reports, re-irradiation with stereotactic body radiotherapy for lung tumors in patients previously treated with thoracic radiation therapy resulted in several serious toxicities. Serious non-lung toxicities were observed mostly in patients with central tumors, but we experienced a case of fatal gastric perforation after a second stereotactic body radiotherapy in a patient w...

The safety and efficacy of carbon-ion radiotherapy for advanced non-small cell lung cancer have not been established. We evaluated the clinical outcomes and dose-volume histogram parameters of carbon-ion radiotherapy compared with photon therapy in T2b-4N0M0 non-small cell lung cancer. Twenty-three patients were treated with carbon-ion radiotherapy between May 2011 and December 2015. Seven, 14,...

Background: Tangential irradiation of intact breast is one of the most common procedures performed in any radiotherapy center. This method is performed by using 2D and 3D treatment planning. The aim of this study was to compare 2D with 3D plans in breast conserving radiotherapy. Homogeneity of isodose, and lung received dose were compared. Materials and Methods: Twenty patients with br...

background: tangential irradiation of intact breast is one of the most common procedures performed in any radiotherapy center. this method is performed by using 2d and 3d treatment planning. the aim of this study was to compare 2d with 3d plans in breast conserving radiotherapy. homogeneity of isodose, and lung received dose were compared. materials and methods: twenty patients with breast canc...

Lung cancer is the leading cause of death due to cancer in China. The annual mortality rate for lung cancer is approximately 456 deaths per million people [1], which means that approximately 600,000 people die from lung cancer every year in China. Radiotherapy is one of the most important modalities for lung cancer treatment. In recent years, great progress has been made in radiotherapy for lun...

Lung injury is one of the major concerns for chest cancer patients that undergo radiotherapy as well as persons exposed to an accidental radiological event. Reduction/oxidation (redox) system plays a key role in lung injury via chronic upregulation of pro-oxidant enzymes. NOX2 and NOX4 are two important reactive oxygen species generating enzymes that are involved in radiation toxicity in some o...

Radiotherapy is the most commonly used treatment modality for patients with lung cancer in the UK, with established, although frequently ignored, indications. It has a role in early, medically inoperable, and locally advanced unresectable non-small cell lung cancer (NSCLC), where some patients are cured, in the palliation of advanced lung cancer of all types, and in the adjuvant treatment of li...

Background: In some patients with stage III small cell lung cancer (SCLC), it is found that the treatment mode of systemic chemotherapy followed by auxiliary radiotherapy better than early radiotherapy, but there no clear evidence-based medical explanation for this. This study was designed to retrospectively evaluate prognostic factors SCLC and explore best locally advanced SCLC.

introduction: breast conserving radiotherapy is one of the most common procedures performed in any radiation oncology department. a tangential parallel-opposed pair is usually used for this purpose. this technique is performed using 2d or 3d treatment planning systems. the aim of this study was to compare 2d treatment planning with 3d treatment planning in tangential irradiation in breast conse...