We present the characteristics of a ventilation-perfusion scan correlating to both planar and single photon emission computed tomography and computed tomography (SPECT/CT) images of the lungs in a patient with SwyerJames (MacLeod) syndrome. A Tc-99m MAA lung perfusion scan was recorded with multiple projections and SPECT/CT. In the ventilation scan, initially dynamic acquisition of aerosol Tc-9...

Introduction: Nuclear Scintigraphy is a highly sensitive, alternative imaging modality used in human and veterinary medicine. This modality involves the administration of a radioactive substance (radioisotope) to a patient. Generally, the radioisotope is labeled to a specific compound. This labeled combination is known as a radiopharmaceutical. These radiopharmaceuticals are formulated in vario...

The use of radionuclide ventilation lung scan to characterise the physiological effects of tracheobronchomalacia is a novel application of this non-invasive technique. In the reported case the right upper lobe was found to be not ventilated below a pressure of 20 cm H2O despite evidence from a dynamic tracheobronchogram of the right upper lobe bronchus opening at the lower pressure of 15 cm H2O.

Bone scanning using the 99mTc-phosphate analogs is an established diagnostic modality and a commonly requested radioisotope examination for a variety of pathologies involving the skeleton, such as osteomyelitis, bony metastases, and occult fractures. The bone scan is one of the most commonly requested procedure in most nuclear medicine department. The images show areas of increased and de...

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Two cases of hypercalcemia associated with transitional cell carcinoma and negative bone scan are described. In both cases hypercalcemia appeared while there was evidence of tumor spread. Although hypercalcemia was controlled, both patients died shortly thereafter. Hypercalcemia rarely occurs in transitional cell carcinoma and its appearance may suggest spreading of the tumor and poor prognosis.

99mTc radiopharmaceuticals play an important role in widespread applications of nuclear medicine. When 99mTc radiopharmaceuticals first came into use, major efforts were directed toward the development of 99mTc radiopharmaceuticals for bone imaging and for the excretory functions of the liver and kidneys. In the past 20 years, a significant advance has been made in technetium chemistry, which p...

Generalized subcutaneous edema is a rare presentation of dermatomyositis. Here, we describe the case of a 57 year-old Hispanic female who presented with dermatomyositis and generalized edema. This case represents the first report of decreased lymphatic drainage, investigated using lymphoscintigraphy in dermatomyositis. Upon reviewing the literature regarding dermatomyositis cases with generaliz...

We prospectively studied 86 children to assess the value and accuracy of isotope bone scanning in the diagnosis of suspected acute haematogenous osteomyelitis and septic arthritis. The patients were scanned because of difficulty in localising the exact site of the pathology. Characteristic scan appearances were found. In osteomyelitis there was increased or decreased uptake extending beyond the...

Two preeminent lymphologists debate the findings, implications, interpretations, and value of magnetic resonance lymphography (MRL) in the evaluation of peripheral lymphedema. Their contrasting views are discussed in the context of different lymphatic imaging modalities including MRL, lymphoscintigraphy, and microscopic anatomy.