context: to evaluate treatment success and hypothyroidism following main methods of radioiodine therapy of toxic nodular goiter (tng); calculated versus fixed dose and high versus low dose of radioiodine. evidence acquisitions: we searched medline and scopus databases from inception till july 2013, for clinical trials that compared two different methods of radioiodine administration in tng. the...

SUMMARY In order to evaluate the long-ter m effects of antithyroids and ahlative therapy on patients with toxic diffuse goiter (TDG) in an iodine deficient region, 206 patients were studied in Tehran. Hyperthyroidism recurred in 50%, of 80 patients treated with Methimazole (MMI), from one week to 48 months after cessation of therapy. Another 40 patients remained in remission. Of 102 patients t...

There are three major therapeutic options for the treatment of Graves' disease (GD): antithyroid drugs (ATDs), thyroidectomy, and radio-iodine (RAI) therapy. ATDs are the initial treatment option for children. However, some pediatric GD patients who are initially treated with ATDs require other type of treatments later on. We reviewed the medical records of childhood-onset GD cases retrospectiv...

10 normal young men received repository epinephrine repeatedly for 4 days during the course of a radiothyroxine (radio-T4) disappearance curve. During epinephrine administration, serum radio-T4 disappearance rate (k) slowed abruptly, fecal clearance decreased, urinary clearance was initially unchanged but later decreased slightly, volume of thyroxine distribution decreased, and external radioac...

[70] Bartsch G, Scheiber K. Tamoxifen Treatment in Oligozoospermia. European Urology. 1981; 7(5): 283-287. and iatrogenic Cushing’s syndrome Cihak RW, Beary FD. Elevated Triiodothyronine and Dextrothyroxine Levels: A Potential Cause of Iatrogenic Hyperthyroidism. Southern Medical Journal. 1977 Feb; 70(2): 256-257. Smidt KP, Johnston E. Undetected Iatrogenic Hypothyroidism: A Late Complication o...

Radioactive iodine therapy is commonly used as an adjuvant therapy in follicular and papillary thyroid carcinoma (PTC) and in the treatment of Graves' disease (GD). The basis of this therapy is the accumulation of radioactive iodine by the sodium-iodide symporter (NIS) in the thyroid gland. Expression of NIS by extrathyroidal tissues such as islets of pancreas has been reported. Radioactive iod...

in research institute for nuclear medicine (tehran university of medical sciences) 50 patients with follicular thyroid carcinoma were evaluted retrospectively. the purpose of the study was assesment of the response of iodine-131 therapy. the best result were achieved when the patient treated with iodine-131 for the first time, in the 4th decade of life, with total thyroidectomy and no metastasi...

Introduction: Earlier studies suggest increased serum levels of thyroid peroxidase antibodies (TPOAb) in some cases with non-autoimmune hyperthyroidism. The aim of the study was to assess the incidence of hypothyroidism in patients with nodular toxic goitre and toxic adenoma at 12 months after radioactive iodine therapy in the relation to TPOAb levels. Patients & Measurements: The study compris...