BACKGROUND: Sphincter preservation, disease control, and long-term survival are the main goals in the treatment of rectal cancer. Although transanal local excision is attractive because it is a sphincter sparing procedure, some contradictory data exist in the literature about its ability to locally control disease and provide overall survival comparable with radical procedures, even for patient...

PURPOSE The proper indication for laparoendoscopic single-site surgery (LESS) in urology is still under debate, especially for malignant diseases. We compared the perioperative outcomes between LESS and conventional laparoscopy (CL) for upper urinary tract malignancies. MATERIALS AND METHODS We reviewed the records of 75 patients who underwent radical nephrectomy, nephroureterectomy with blad...

A 24 year old woman with Gardner's syndrome developed a massive chest wall desmoid tumour, which required radical excision and prosthetic reconstruction. In view of the local aggressiveness of this tumour and the fact that it does not metastasize a policy of radical surgery when possible is recommended.

1. There have been no randomised trials comparing brachytherapy or IMRT with conventional radiotherapy. 2. ADJUVANT radiotherapy has recently been shown to improve progression-free survival after radical surgery in patients with tumour at excision margins or infiltrating seminal vesicles. 3. Hormone therapy improves outcomes (progression free survival and survival) after radical radiotherapy fo...

1. There have been no randomised trials comparing brachytherapy or IMRT with conventional radiotherapy. 2. ADJUVANT radiotherapy has recently been shown to improve progression-free survival after radical surgery in patients with tumour at excision margins or infiltrating seminal vesicles. 3. Hormone therapy improves outcomes (progression free survival and survival) after radical radiotherapy fo...

calcifying odontogenic cyst (coc) is a unique odontogenic lesion with combined features of a cyst and neoplasm.  this lesion shows a great diversity in its clinicopathological behavior.  it may become aggressive and rarely malignant.  this case is an aggressive coc of the maxilla in a young male patient which recurred after several radical surgical excisions.  eventually invading the cranium, t...

calcifying epithelial odontogenic tumor (ceot) is an uncommon odontogenic tumor with well-known histopathological features and a challenging treatment plan. although some investigators advocate conservative approach as the treatment of choice, others believe in radical surgical excision to avoid recurrence or malignant transformation. the main objective of this case report is presenting an unus...