Sera from patients with chronic Chagas heart disease recognize the carboxyl-terminal regions of the Trypanosoma cruzi ribosomal P proteins defined by B cell epitopes P013 (EDDDDDFGMGALF) and R13 (EEEDDDMGFGLFD) corresponding to the T. cruzi ribosomal P0 (TcP0) and P2beta (TcP2beta) proteins, respectively. It has been hypothesized that both epitopes may induce antibodies that cross-react and sti...

We studied the macrophage (Mo) activation pathways through Mo interaction with immunogenic Trypanosoma cruzi antigens as cruzipain (Cz) and R13. J774 cells, peritoneal and spleen Mo from normal mice, were used. Although Mo classic activation was observed in the presence of lipopolysaccharide, evaluated through nitric oxide (NO) and interleukin (IL)-12 production, Cz and R13 did not activate Mo ...

Abstract After 23 years, since the NIH recognized need to increase contribution of underrepresented minority (URM) scientists in biomedical sciences, modest gains have been made address significant under-representation sciences. By time URM scholars gained necessary research skills succeed as scientists, they overcome many social and professional barriers, yet still experience burdens disadvant...

i n the past decades, the effect of different tax amendments on various economic issues has been studied. the majority of these studies have avoided considering shadow economy as part of the calculation and analysis, and an issue, which has received little attention, is the relationship between green tax reforms and shadow economy, as for informal labor, which is well-connected to unemployment ...

Two new problems of bivalent propositional logic are proposed here: firstly, to distinguish the sense of propositions, besides the logical value and secondly, to analyze the ”ponderal” difference between two parts of a proposition: subject-predicate. 1 Relational projections and extensions Let r = (A1, A2, A3, R) be a ternary relation (see [3]). Starting with this, we may define three binary re...

This talk is inspired by two previous ICM talks, by V. Drinfeld (1986), and G.Felder (1994). Namely, one of the main ideas of Drinfeld’s talk is that the quantum Yang-Baxter equation, which is an important equation arising in quantum field theory and statistical mechanics, is best understood within the framework of Hopf algebras, or quantum groups. On the other hand, in Felder’s talk, it is exp...

The cleavage reaction catalyzed by the trans -acting genomic ribozyme of human hepatitis delta virus (HDV) was analyzed with a 13mer substrate (R13) and thio-substituted [SR13(Rp) and SR13(Sp)] substrates under single-turnover conditions. The cleavage of RNA by the trans -acting HDV ribozyme proceeded as a first order reaction. The logarithm of the rate of cleavage (kclv) increased linearly (wi...